J
J. Pijpe
Researcher at University Medical Center Groningen
Publications - 31
Citations - 1746
J. Pijpe is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Rituximab & Parotid gland. The author has an hindex of 12, co-authored 30 publications receiving 1647 citations.
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Journal ArticleDOI
Rituximab treatment in patients with primary Sjögren's syndrome: an open-label phase II study.
J. Pijpe,van Gustaaf Imhoff,Frederik Spijkervet,Jan L. N. Roodenburg,Gerrit Jan Wolbink,K Mansour,Arjan Vissink,Cornelis Kallenberg,Hendrika Bootsma +8 more
TL;DR: Findings of this phase II study suggest that rituximab is effective in the treatment of primary SS and MALT/primary SS and the high incidence of HACAs and associated side effects observed in this study needs further evaluation.
Journal ArticleDOI
Salivary proteomic and genomic biomarkers for primary sjögren's syndrome
Shen Hu,Jianghua Wang,Jiska Meijer,Sonya Ieong,Yongming Xie,Tianwei Yu,Hui Zhou,Sharon Henry,Arjan Vissink,J. Pijpe,Cees G. M. Kallenberg,David Elashoff,Joseph A. Loo,David T.W. Wong +13 more
TL;DR: It is found that WS contains more informative proteins, peptides, and mRNA, as compared with gland-specific saliva, that can be used in generating candidate biomarkers for the detection of primary SS.
Journal ArticleDOI
Parotid gland biopsy compared with labial biopsy in the diagnosis of patients with primary Sjogren's syndrome
J. Pijpe,Warner Kalk,J.E. van der Wal,Arjan Vissink,Philippus Kluin,Jan L. N. Roodenburg,Hendrika Bootsma,Cornelis Kallenberg,Frederik Spijkervet +8 more
TL;DR: A parotid biopsy has a diagnostic potential comparable with that of a labial biopsy in the diagnosis of pSS, and may be associated with less morbidity.
Journal ArticleDOI
Progression of salivary gland dysfunction in patients with Sjögren's syndrome
TL;DR: Early Sjögren’s syndrome is characterised by a decreased salivary gland function (parotis>SM/SL), which shows a further decrease over time, regardless of the use of DMARDs or steroids.
Journal ArticleDOI
Changes in salivary gland immunohistology and function after rituximab monotherapy in a patient with Sjögren’s syndrome and associated MALT lymphoma
J. Pijpe,G. W. van Imhoff,Arjan Vissink,J.E. van der Wal,Philip M. Kluin,Fred K. L. Spijkervet,C. G. M. Kallenberg,Hendrika Bootsma +7 more
TL;DR: This case report is the first to describe the effect of rituximab on histological and sialometric/chemical characteristics of SS, and is a promising agent in the treatment of SS associated MALT lymphoma.