F
Fred K. L. Spijkervet
Researcher at University Medical Center Groningen
Publications - 33
Citations - 3431
Fred K. L. Spijkervet is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Cancer & Mucositis. The author has an hindex of 24, co-authored 29 publications receiving 3082 citations. Previous affiliations of Fred K. L. Spijkervet include University of Groningen.
Papers
More filters
Journal ArticleDOI
Effectiveness of rituximab treatment in primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled trial.
Jiska Meijer,Petra M. Meiners,Arjan Vissink,Fred K. L. Spijkervet,Wayel H. Abdulahad,N. Kamminga,Elisabeth Brouwer,Cees G. M. Kallenberg,Hendrika Bootsma +8 more
TL;DR: Rituximab treatment is an effective and safe treatment strategy for patients with primary Sjögren's syndrome and significant improvements were found in comparison with baseline values.
Journal ArticleDOI
Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: Demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life
Linda S. Elting,Dorothy M. K. Keefe,Stephen T. Sonis,Adam S. Garden,Fred K. L. Spijkervet,Andrei Barasch,Roy B. Tishler,Thomas P. Canty,Mahesh K. Kudrimoti,Montserrat Vera-Llonch +9 more
TL;DR: The risk, severity, and patient-reported outcomes of radiation-induced mucositis among head and neck cancer patients were prospectively estimated in this article, and the detrimental effects on QOL and functional status are significant, and opioid analgesia provides inadequate relief.
Journal ArticleDOI
A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: management strategies and economic impact
Siri Beier Jensen,Anne Marie Lynge Pedersen,Arjan Vissink,Elo Andersen,Carlton G. Brown,Andrew Davies,J. Dutilh,Janet S. Fulton,Ljiljana Janković,Nilza Nelly Fontana Lopes,A. L. S. Mello,L. V. Muniz,C. A. Murdoch-Kinch,Raj G. Nair,Joel J. Napeñas,A. Nogueira-Rodrigues,Deborah P. Saunders,B. Stirling,I. von Bültzingslöwen,Dianna Weikel,Linda S. Elting,Fred K. L. Spijkervet,Michael T. Brennan,Salivary Gland Hypofunction,Xerostomia Section +24 more
TL;DR: There is evidence that salivary gland hypofunction and xerostomia induced by cancer therapies can be prevented or symptoms be minimized to some degree, depending on the type of cancer treatment.
Journal ArticleDOI
A systematic review of dental disease in patients undergoing cancer therapy
Catherine H.L. Hong,Joel J. Napeñas,Brian D. Hodgson,Monique A. Stokman,Vickie Mathers-Stauffer,Linda S. Elting,Fred K. L. Spijkervet,Michael T. Brennan +7 more
TL;DR: Patients who were post-radiotherapy had the highest DMFT and the use of fluoride products and chlorhexidine rinses are beneficial in patients who are post- Radiotherapy.
Journal ArticleDOI
A systematic review of oral fungal infections in patients receiving cancer therapy
Rajesh V. Lalla,Marie C. Latortue,Catherine H.L. Hong,Anura Ariyawardana,Sandra D'Amato-Palumbo,Dena J. Fischer,Andrew Martof,Ourania Nicolatou-Galitis,Lauren L. Patton,Linda S. Elting,Fred K. L. Spijkervet,Michael T. Brennan +11 more
TL;DR: There is an increased risk of clinically significant oral fungal infection during cancer therapy, and systemic antifungals are effective in the prevention of clinical oralFungal infection in patients receiving cancer therapy.