J
J.R. Brook
Researcher at University of Toronto
Publications - 14
Citations - 614
J.R. Brook is an academic researcher from University of Toronto. The author has contributed to research in topics: Gut flora & Cohort. The author has an hindex of 7, co-authored 14 publications receiving 352 citations. Previous affiliations of J.R. Brook include Environment Canada.
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Journal ArticleDOI
Predicting the atopic march: Results from the Canadian Healthy Infant Longitudinal Development Study.
Maxwell M. Tran,Diana L. Lefebvre,Christoffer Dharma,David Dai,Wendy Y. W. Lou,Padmaja Subbarao,Allan B. Becker,Piush J. Mandhane,Stuart E. Turvey,Malcolm R. Sears,P. Subbarao,S.E. Turvey,Sonia S. Anand,M.B. Azad,A.B. Becker,A D Befus,Michael Brauer,J.R. Brook,Edith Chen,Michael M Cyr,Denise Daley,Sharon D. Dell,Judah A. Denburg,Q. L. Duan,Thomas Eiwegger,Hartmut Grasemann,Kent T. HayGlass,Richard G. Hegele,D. L. Holness,Perry Hystad,Michael S. Kobor,Tobias R. Kollmann,Anita L. Kozyrskyj,Catherine Laprise,W.Y.W. Lou,Joseph Macri,P. J. Mandhane,Gregory E. Miller,Theo J Moraes,Peter D. Paré,Clare D. Ramsey,Felix Ratjen,Andrew J. Sandford,James A. Scott,James Scott,M.R. Sears,Frances Silverman,Elinor Simons,Timothy K. Takaro,Scott Sj Tebbutt,Teresa To +50 more
TL;DR: Atopic dermatitis without concomitant allergic sensitization was not associated with an increased risk of asthma at age 3 years after adjusting for common confounders, and in combination, atopy dermatitis and allergy sensitization had strong interactive effects on both asthma and food allergy risk at age3 years.
Journal ArticleDOI
Fecal Short-Chain Fatty Acid Variations by Breastfeeding Status in Infants at 4 Months: Differences in Relative versus Absolute Concentrations.
Sarah L. Bridgman,Meghan B. Azad,Catherine J. Field,Andrea M. Haqq,Allan B. Becker,Piushkumar J. Mandhane,Padmaja Subbarao,Stuart E. Turvey,Malcolm R. Sears,James A. Scott,David S. Wishart,Anita L. Kozyrskyj,M.R. Sears,P. Subbarao,Sonia S. Anand,M.B. Azad,A.B. Becker,A D Befus,Michael Brauer,J.R. Brook,Edith Chen,Michael M Cyr,Denise Daley,Sharon D. Dell,Judah A. Denburg,Q. L. Duan,Thomas Eiwegger,Hartmut Grasemann,Kent T. HayGlass,Richard G. Hegele,D. L. Holness,Perry Hystad,Michael S. Kobor,T. R. Kollman,Anita L. Kozyrskyj,Catherine Laprise,Wendy Y. W. Lou,Joseph Macri,Piush J. Mandhane,Gregory E. Miller,Theo J Moraes,Peter D. Paré,Clare D. Ramsey,Felix Ratjen,Andrew J. Sandford,James Scott,Jeremy A. Scott,Frances Silverman,Elinor Simons,Timothy K. Takaro,Scott J. Tebbutt,Teresa To,S.E. Turvey +52 more
TL;DR: It is confirmed that breastfeeding strongly influences the composition of fecal microbial metabolites in infancy and those exclusively breastfed were four times more likely to have a higher proportion of acetate relative to other SCFAs in their gut.
Journal ArticleDOI
Monthly Global Estimates of Fine Particulate Matter and Their Uncertainty.
Aaron van Donkelaar,Aaron van Donkelaar,Melanie S. Hammer,Liam Bindle,Michael Brauer,Michael Brauer,J.R. Brook,Michael J. Garay,N. Christina Hsu,Olga V. Kalashnikova,Ralph A. Kahn,Colin J. Lee,Robert C. Levy,Alexei Lyapustin,Andrew M. Sayer,Andrew M. Sayer,Randall V. Martin,Randall V. Martin +17 more
TL;DR: In this paper, the authors developed and applied a methodology for monthly estimates and uncertainties during the period 1998-2019, which combines satellite retrievals of aerosol optical depth, chemical transport modeling, and ground-based measurements to allow for the characterization of seasonal and episodic exposure, as well as aid air-quality management.
Journal ArticleDOI
SPARTAN: a global network to evaluate and enhance satellite-based estimates of ground-level particulate matter for global health applications
Graydon Snider,Crystal L. Weagle,Randall V. Martin,Randall V. Martin,A. van Donkelaar,K. Conrad,D. J. M. Cunningham,C. Gordon,M. Zwicker,Clement Akoshile,Paulo Artaxo,Nguyen Xuan Anh,J.R. Brook,Jinlu Dong,Rebecca M. Garland,R. Greenwald,D. Griffith,K. B. He,Brent N. Holben,Ralph A. Kahn,Ilan Koren,Nofel Lagrosas,Puji Lestari,Zongwei Ma,J. Vanderlei Martins,Eduardo Quel,Yinon Rudich,Abdus Salam,Sachchida Nand Tripathi,Chao Yu,Qiang Zhang,Yinping Zhang,Michael Brauer,Aaron Cohen,Mark D. Gibson,Yang Liu +35 more
TL;DR: The Surface Particulate mAtter Network (SPARTAN) as discussed by the authors is a global network of ground-level monitoring stations designed to evaluate and enhance satellite remote sensing estimates for application in health effects research and risk assessment.
Journal ArticleDOI
Cesarean Section, Formula Feeding, and Infant Antibiotic Exposure: Separate and Combined Impacts on Gut Microbial Changes in Later Infancy.
Farzana Yasmin,Hein M. Tun,Theodore Konya,David S. Guttman,Radha Chari,Catherine J. Field,Allan B. Becker,Piush J. Mandhane,Stuart E. Turvey,Padmaja Subbarao,Malcolm R. Sears,Child Study Investigators,James A. Scott,Irina Dinu,Anita L. Kozyrskyj,Sonia S. Anand,M.B. Azad,A.B. Becker,A D Befus,Michael Brauer,J.R. Brook,Edith Chen,Michael M Cyr,Denise Daley,Sharon D. Dell,Judah A. Denburg,Q. L. Duan,Thomas Eiwegger,Hartmut Grasemann,Kent T. HayGlass,Richard G. Hegele,D. L. Holness,Perry Hystad,Michael S. Kobor,Tobias R. Kollmann,Anita L. Kozyrskyj,Catherine Laprise,Wendy Y. W. Lou,Joseph Macri,P. J. Mandhane,Gregory E. Miller,Theo J Moraes,Peter D. Paré,Clare D. Ramsey,Felix Ratjen,Andrew J. Sandford,James Scott,Jeremy A. Scott,M.R. Sears,Frances Silverman,Elinor Simons,P. Subbarao,Timothy K. Takaro,Scott J. Tebbutt,Teresa To,S.E. Turvey +55 more
TL;DR: Gut microbiota of infants born vaginally and exclusively formula fed became less enriched with family Veillonellaceae and Clostridiaceae, showed unchanging levels of Ruminococcaceae, and exhibited a greater decline in the Rikenellaceae/Bacteroids ratio compared to their breastfed, vaginally delivered counterparts.