J
J. R. Siewert
Researcher at Technische Universität München
Publications - 392
Citations - 17274
J. R. Siewert is an academic researcher from Technische Universität München. The author has contributed to research in topics: Cancer & Adenocarcinoma. The author has an hindex of 68, co-authored 391 publications receiving 16687 citations. Previous affiliations of J. R. Siewert include Ludwig Maximilian University of Munich & Heidelberg University.
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Journal ArticleDOI
Prognosis of patients with colorectal cancer is associated with lymph node ratio: a single-center analysis of 3,026 patients over a 25-year time period.
Robert Rosenberg,Jan Friederichs,Tibor Schuster,Ralf Gertler,Matthias Maak,Karen Becker,Anne Grebner,Kurt Ulm,Heinz Höfler,Hjalmar Nekarda,J. R. Siewert +10 more
TL;DR: The defined cut-off values of LNRs were strong independent prognostic factors for colorectal cancer patients and should be calculated for risk group stratification.
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Bile reflux in benign and malignant Barrett's esophagus: effect of medical acid suppression and Nissen fundoplication☆
TL;DR: Bile reflux into the esophagus can be completely suppressed by Nissen fundoplication but not medical acid suppression alone, and in patients with early carcinoma in Barrett’sEsophageal bile exposure time showed an exponential increase from GERD patients without esophagitis to those with erosive esphagitis and benign Barrett”s Esophagus.
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Essential Role of Gamma Interferon in Survival of Colon Ascendens Stent Peritonitis, a Novel Murine Model of Abdominal Sepsis
Niko Zantl,Annette Uebe,Brigitte Neumann,Hermann Wagner,J. R. Siewert,Bernhard Holzmann,Claus-Dieter Heidecke,Klaus Pfeffer +7 more
TL;DR: A novel animal model that closely mimics human sepsis and appears to be highly suitable for the study of the pathophysiology of abdominal sepsi is described, and this model demonstrates a protective role of IFN-γ in survival of bacterial sePSis.
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Stented versus nonstented pancreaticojejunostomy after pancreatoduodenectomy: a prospective study.
TL;DR: In this nonrandomized prospective observational study, temporary external drainage of the pancreatic duct with a PVC tube significantly reduced the leakage rate of the Pancicojejunostomy as well as the duration of hospital stay after partial pancreatoduodenectomy.
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Selective defects of T lymphocyte function in patients with lethal intraabdominal infection
Claus-Dieter Heidecke,Thorsten Hensler,Heike Weighardt,Niko Zantl,Hermann Wagner,J. R. Siewert,Bernhard Holzmann +6 more
TL;DR: Defective T-cell proliferation and secretion of IL-2 and TNF correlate with sepsis mortality, thus indicating an important role of T 'cells for the immune defense against postoperative infection.