H
Heinz Höfler
Researcher at Technische Universität München
Publications - 377
Citations - 20136
Heinz Höfler is an academic researcher from Technische Universität München. The author has contributed to research in topics: Cancer & Adenocarcinoma. The author has an hindex of 74, co-authored 377 publications receiving 19163 citations. Previous affiliations of Heinz Höfler include Ludwig Maximilian University of Munich & Helmholtz Zentrum München.
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Journal ArticleDOI
Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy.
Karen Becker,James Mueller,Christoph Schulmacher,Katja Ott,Ulrich Fink,Raymonde Busch,K. Böttcher,J. Rüdiger Siewert,Heinz Höfler +8 more
TL;DR: The authors performed the current study to determine which histomorphologic features are correlated with patient prognosis after chemotherapy, and which are not.
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Mutations of the human E‐cadherin (CDH1) gene
TL;DR: Inactivating germline mutations of E‐cadherin were recently reported for families with early‐onset diffuse gastric cancer, suggesting loss of growth control by such mutations and defining E‐ cadher in as a true tumor suppressor for these particular tumor types.
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Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.
Natalia S. Pellegata,Leticia Quintanilla-Martinez,Heide Siggelkow,Elenore Samson,Karin Bink,Heinz Höfler,Falko Fend,Jochen Graw,Michael J. Atkinson +8 more
TL;DR: The findings demonstrate that germ-line mutations in p27Kip1 can predispose to the development of multiple endocrine tumors in both rats and humans.
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Revised classification of neuroendocrine tumours of the lung, pancreas and gut.
TL;DR: New classifications of the neuroendocrine tumours of the lung, pancreas and gut are proposed and attempt to consider the morphological, functional as well as biological features of the tumours.
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HER2 diagnostics in gastric cancer—guideline validation and development of standardized immunohistochemical testing
Josef Rüschoff,Manfred Dietel,Gustavo B. Baretton,Susanne Arbogast,Axel Walch,Geneviève Monges,Marie-Pierre Chenard,Frédérique Penault-Llorca,Iris Nagelmeier,W. Schlake,Heinz Höfler,H.H. Kreipe +11 more
TL;DR: To validate this new HER2 status testing procedure in terms of inter-laboratory and inter-observer consensus for IHC scoring a series of 547 gastric cancer tissue samples on a tissue microarray (TMA) was used.