J
J. Reventós
Researcher at Hebron University
Publications - 16
Citations - 975
J. Reventós is an academic researcher from Hebron University. The author has contributed to research in topics: Endometrial cancer & Cancer. The author has an hindex of 14, co-authored 16 publications receiving 920 citations. Previous affiliations of J. Reventós include Hospital Universitari Arnau de Vilanova.
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Journal ArticleDOI
Novel molecular profiles of endometrial cancer-new light through old windows.
Andreas Doll,Miguel Abal,Marina Rigau,Marta Monge,M. Gonzalez,Santiago Demajo,Eva Colas,Marta Llauradó,H. Alazzouzi,J. Planagumá,M.A. Lohmann,J. Garcia,S. Castellvi,J. Ramon y Cajal,Antonio Gil-Moreno,Jordi Xercavins,F. Alameda,J. Reventós +17 more
TL;DR: Despite the great effort made to establish a molecularly-based histological classification, the following issues must still be clarified: what triggers the tumor cells to invade the myometrium and what causes vascular or lymphatic dissemination, finally culminating in metastasis?
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Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetrahydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility
TL;DR: It is suggested that polymorphisms at MTHFR and a novel CYP1A1 variant could influence susceptibility to endometrial cancer, although larger sample sizes would be required to corroborate these findings.
Journal ArticleDOI
Endometrial carcinoma: molecular alterations involved in tumor development and progression.
Andree Yeramian,Gema Moreno-Bueno,Xavier Dolcet,Lluis Catasus,Miguel Abal,Eva Colás,J. Reventós,José Palacios,Jaime Prat,Xavier Matias-Guiu +9 more
TL;DR: In this review, the genetic changes of endometrial carcinogenesis are discussed in the light of the morphological features of the tumors and their precursors.
Journal ArticleDOI
Susceptibility to endometrial cancer: influence of allelism at p53, glutathione S-transferase (GSTM1 and GSTT1) and cytochrome P-450 (CYP1A1) loci.
TL;DR: An insertional variant in p53 (P53PIN3) and two polymorphisms in the 3'-end and exon 7 of CYP1A1 showed significant association with enhanced endometrial cancer risk.
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Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma
Jesús Planagumà,Jesús Planagumà,Mikko Liljeström,Francesc Alameda,Ralf Bützow,Ismo Virtanen,J. Reventós,Mika Hukkanen +7 more
TL;DR: Results indicate concurrent mechanisms in expression of MMP-2 and -9, RUNX1/AML1 and ETV5/ERM, and several of the basement membrane components, which are likely to associate with the invasive stage of EEC and OEC.