G
Gema Moreno-Bueno
Researcher at University of Texas MD Anderson Cancer Center
Publications - 158
Citations - 15025
Gema Moreno-Bueno is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 59, co-authored 138 publications receiving 13212 citations. Previous affiliations of Gema Moreno-Bueno include Autonomous University of Barcelona & Complutense University of Madrid.
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Journal ArticleDOI
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Héctor Peinado,Maša Alečković,Simon Lavotshkin,Irina Matei,Bruno Costa-Silva,Gema Moreno-Bueno,Marta Hergueta-Redondo,Caitlin Williams,Guillermo García-Santos,Cyrus M. Ghajar,Ayuko Nitadori-Hoshino,Caitlin Hoffman,Karen Badal,Benjamin A. Garcia,Margaret K. Callahan,Jianda Yuan,Vilma R. Martins,Johan Skog,Rosandra N. Kaplan,Mary S. Brady,Jedd D. Wolchok,Jedd D. Wolchok,Paul B. Chapman,Paul B. Chapman,Yibin Kang,Yibin Kang,Jacqueline Bromberg,Jacqueline Bromberg,David Lyden +28 more
TL;DR: The data show that exosome production, transfer and education of bone marrow cells supports tumor growth and metastasis, has prognostic value and offers promise for new therapeutic directions in the metastatic process.
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Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype
David Sarrió,Socorro María Rodríguez-Pinilla,David Hardisson,Amparo Cano,Gema Moreno-Bueno,José Palacios +5 more
TL;DR: The data indicate that in breast tumors, EMT likely occurs within a specific genetic context, the basal phenotype, and suggests that this proclivity to mesenchymal transition may be related to the high aggressiveness and the characteristic metastatic spread of these tumors.
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Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
Oscar H. Ocaña,Rebeca Córcoles,Angels Fabra,Gema Moreno-Bueno,Gema Moreno-Bueno,Hervé Acloque,Sonia Vega,Alejandro Barrallo-Gimeno,Amparo Cano,M. Angela Nieto +9 more
TL;DR: It is shown that the homeobox factor Prrx1 is an EMT inducer conferring migratory and invasive properties, and is a biomarker associated with patient survival and lack of metastasis.
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Correlation of Snail expression with histological grade and lymph node status in breast carcinomas.
Maria Blanco,Gema Moreno-Bueno,David Sarrió,Annamaria Locascio,Amparo Cano,José Palacios,M. Angela Nieto +6 more
TL;DR: It is shown that Snail expression inversely correlates with the grade of differentiation of the tumours and that it is expressed in all the infiltrating ductal carcinomas presenting lymph node metastases that were analysed.
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Transcriptional regulation of cell polarity in EMT and cancer.
TL;DR: Re-examined data related to the effect of EMT related transcription factors on epithelial cell plasticity and genetic interactions that highlight the existence of complex regulatory networks converging on the regulation of cell polarity by EMT inducers in human breast carcinomas are analyzed.