J.T. McClure

TL;DR: Herd-level milk production was positively associated with overall ADUR, ADUR of systemically administered ceftiofur, cephapirin administered for dry cow therapy, and pirlimycin administered for clinical mastitis treatment, and β-lactams were most commonly used on Canadian dairy farms.

TL;DR: Prevalence of AMR in bovine mastitis pathogens was low; most gram-negative udder pathogens were multidrug resistant; MRSA was rarely found, and ESBL E. coli and Klebsiella species isolates were absent in Canadian milk samples.

TL;DR: Herd-level use of certain antimicrobials administered for mastitis treatment and control, such as intramammary penicillin and pirlimycin as well as systemically administered penichill and florfenicol, was positively associated with antimicrobial resistance in bovine mastitis pathogens in the field conditions.

TL;DR: The prevalence of Mycobacterium avium ssp.

TL;DR: Enrofloxacin killing of E coli and staphylococci is concentration dependent and not time dependent, and pharmacokinetic values analyzed by use of multivariant stepwise linear regression analysis indicated that the area under the concentration-time curve, but not time above minimum inhibitory concentration, was significant in predicting efficacy of enrofl oxacin treatment.