Jack H. Freed

TL;DR: In this paper, a model for describing the dynamics of flexible alkyl chains that is based on Flory's rotational isomeric state approximation is adapted and applied to the analysis of electron spin resonance (ESR) spectra obtained from a phospholipid spin label in a macroscopically aligned polysilicon membrane.

TL;DR: In this paper, the Pulse-Dipolar ESR Spectroscopies (PDS) were proposed for electron spin resonance (ESR) spectroscopy and compared with double quantum coherence (DQC)-ESR and doubleelectron-electron resonance (DEER) methods.

TL;DR: A 250-GHz electron spin resonance (ESR) study of macroscopically aligned model membranes composed of mixtures of dimyristoylphosphatidylcholine and DMPC, utilizing the nixtroxide-labeled cholesterol analog cholestane (CSL), implies that the inefficient packing between cholesterol and DMPS occurs probably because of the strong interactions between the PS headgroups, which provide the local biaxiality.

TL;DR: ESR microscopy as mentioned in this paper uses an image probe comprising gradient coils in addition to conventional modulation coils or magnetic field bias coils (in pulse mode), and a resonator constructed from high permittivity material.

TL;DR: It is shown that calcium directly targets the Ebola virus fusion peptide and influences its conformation, and mechanistic insight provides a rationale for the use of calcium-interfering drugs already approved by the FDA as therapeutics against Ebola and enables further development of novel drugs to combat the virus.