J
Jack H. Freed
Researcher at Cornell University
Publications - 468
Citations - 24789
Jack H. Freed is an academic researcher from Cornell University. The author has contributed to research in topics: Electron paramagnetic resonance & Relaxation (NMR). The author has an hindex of 82, co-authored 459 publications receiving 23392 citations. Previous affiliations of Jack H. Freed include Dartmouth College & University of Freiburg.
Papers
More filters
Journal ArticleDOI
Conformational Dynamics in Extended RGD-Containing Peptides.
William R. Lindemann,Alexander J. Mijalis,José Luis Alonso,Peter P. Borbat,Jack H. Freed,M. Amin Arnaout,Bradley L. Pentelute,Julia H. Ortony +7 more
TL;DR: It is found that disorder of the binding site is important to the potency of RGD peptides, and that transient hydrogen bonding near the RGD site affects both the energy landscape roughness of the peptides and peptide binding.
Journal ArticleDOI
Deuterium NMR study of the structure and dynamic of the side chains of several solid polyglutamates
Eva Meirovitch,Edward T. Samulski,Andrew R. Leed,Harold A. Scheraga,Shankar B. Rananavare,George Nemethy,Jack H. Freed +6 more
TL;DR: In this article, a /sup 2/H NMR study of polycrystalline powders and oriented films of several selectively deuterium-labeled poly(..gamma..-benzyl L-glutamate) (PBLG) and poly(.gamma,.-ethyl L-lglutamide) homopolymers is reported.
Journal ArticleDOI
Theory of Spin Relaxation via Quantum-Molecular Systems: Resonance Effects
TL;DR: In this article, a relaxation equation for the spin density matrix is derived on the assumptions that the spins are weakly coupled to the molecular degrees of freedom which are described quantum mechanically and the relaxation of the molecular systems is well represented by a general time-independent relaxation matrix which can include effects of weak as well as strong collisions.
Journal ArticleDOI
The internal dynamics of mini c TAR DNA probed by electron paramagnetic resonance of nitroxide spin-labels at the lower stem, the loop, and the bulge.
Yan Sun,Ziwei Zhang,Vladimir M. Grigoryants,William K. Myers,Fei Liu,Keith Earle,Jack H. Freed,Charles P. Scholes +7 more
TL;DR: Electron paramagnetic resonance (EPR) at 236.6 and 9.5 GHz probed the tumbling of nitroxide spin probes in the lower stem, in the upper loop, and near the bulge of mini c TAR DNA, finding the slowing of nanosecond motions of large segments of the oligonucleotide was enhanced by increasing the ratio of the nucleocapsid protein NCp7 to mini cTAR DNA from 0 to 2.