J
Jack Jallo
Researcher at Temple University
Publications - 23
Citations - 1542
Jack Jallo is an academic researcher from Temple University. The author has contributed to research in topics: Spinal cord injury & Hypertonic saline. The author has an hindex of 10, co-authored 22 publications receiving 1491 citations. Previous affiliations of Jack Jallo include Thomas Jefferson University.
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Journal ArticleDOI
Clinical trials in head injury
Raj K. Narayan,Mary Ellen Michel,Beth Ansell,Alex Baethmann,Anat Biegon,Michael B. Bracken,M. Ross Bullock,Sung C. Choi,Guy L. Clifton,Charles F. Contant,William M. Coplin,W. Dalton Dietrich,Jamshid Ghajar,Sean M. Grady,Robert G. Grossman,Edward D. Hall,William Heetderks,David A. Hovda,Jack Jallo,Russell L. Katz,Nachshon Knoller,Patrick M. Kochanek,Andrew I R Maas,Jeannine Majde,Donald W. Marion,A Marmarou,Lawrence F. Marshall,Tracy K. McIntosh,Emmy Miller,Noel Mohberg,J. Paul Muizelaar,Lawrence H. Pitts,Peter Quinn,Gad Riesenfeld,Claudia S. Robertson,Kenneth I. Strauss,Graham M. Teasdale,Nancy Temkin,Ronald F. Tuma,Charles E. Wade,Michael D. Walker,Michael Weinrich,John Whyte,Jack E. Wilberger,A. Byron Young,Lorraine Yurkewicz +45 more
TL;DR: The pathomechanisms of traumatic brain damage, based upon their clinical importance, are discussed and a uniform strategic approach for evaluation of potentially interesting new compounds in clinical trials, to ameliorate outcome in patients with severe head injury, is proposed.
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Cannabinoid CB2 receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model
TL;DR: CB2 activation is associated with a Reduction in white blood cell rolling and adhesion along cerebral vascular endothelial cells, a reduction in infarct size, and improved motor function after transient focal ischemia.
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Intravital Fluorescence Microscopy: Impact of Light-induced Phototoxicity on Adhesion of Fluorescently Labeled Leukocytes
R. K. Saetzler,Jack Jallo,H. A. Lehr,C.M. Philips,Usha S. Vasthare,Karl E. Arfors,Ronald F. Tuma +6 more
TL;DR: This study underscores the necessity to optimize microscopic set-ups for intravital microscopy, to reduce the excitation light energy level significantly, and to perform stringent control experiments, ruling out an artificial phototoxicity-induced stimulation of leukocyte adhesion.
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CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury
TL;DR: CB(2) activation contributed to protecting the brain through the attenuation of cerebral microcirculatory dysfunction during cerebral I/R injury by exerted optimal effects in reducing cerebral infarction and improving neurological function compared with other dosage groups and control group.
Journal ArticleDOI
Hypertonic saline: a clinical review
TL;DR: Mechanisms of action, adverse effects, and current clinical studies show that HTS administered during the resuscitation of patients with a TBI improves neurological outcome and the role of HTS in prehospital resuscitation is yet to be determined.