J
Jack M. Guralnik
Researcher at University of Maryland, Baltimore
Publications - 472
Citations - 90624
Jack M. Guralnik is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Population & Anemia. The author has an hindex of 148, co-authored 453 publications receiving 83701 citations. Previous affiliations of Jack M. Guralnik include National Institutes of Health & University of Florida.
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Journal ArticleDOI
Coimpairments as predictors of severe walking disability in older women.
Taina Rantanen,Jack M. Guralnik,Luigi Ferrucci,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Suzanne G. Leveille,Sarianna Sipilä,Sarianna Sipilä,Linda P. Fried +8 more
TL;DR: The aim of this study was to determine the combined effects of two impairments, decreased knee‐extension strength and poor standing balance, on the risk of developing severe walking disability among older, moderately‐to‐severely disabled women who did not have severe Walking disability at baseline.
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High-Frequency Vibration Training Increases Muscle Power in Postmenopausal Women
Cosimo Roberto Russo,Fulvio Lauretani,Stefania Bandinelli,Benedetta Bartali,Chiara Cavazzini,Jack M. Guralnik,Luigi Ferrucci +6 more
TL;DR: Reflex muscular contractions induced by vibration training improve muscle power in postmenopausal women and no significant changes were observed in bone characteristics.
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Low testosterone levels and the risk of anemia in older men and women
Luigi Ferrucci,Marcello Maggio,Stefania Bandinelli,Shehzad Basaria,Fulvio Lauretani,Alessandro Ble,Giorgio Valenti,William B. Ershler,Jack M. Guralnik,Dan L. Longo +9 more
TL;DR: Older men and women with low testosterone levels have a higher risk of anemia, and total and bioavailable testosterone levels were associated with hemoglobin levels in women and in men.
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Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing
Lorna W. Harries,Dena G. Hernandez,William Henley,Andrew R. Wood,Alice C. Holly,Rachel M. Bradley-Smith,Hanieh Yaghootkar,Ambarish Dutta,Anna Murray,Timothy M. Frayling,Jack M. Guralnik,Stefania Bandinelli,Andrew B. Singleton,Luigi Ferrucci,David Melzer +14 more
TL;DR: Human peripheral blood leukocyte in‐vivo RNA is examined in a large‐scale transcriptomic microarray study, suggesting that modification of mRNA processing may be a feature of human aging.
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Assessing the impact of comorbidity in the older population
TL;DR: Two general approaches have been used to incorporate disease severity measures into comorbidity indices: assignment of severity scores to all relevant conditions with summation of these scores, and assignment of comor bidity severity based on the most severeComorbid disease present.