J
Jack M. Guralnik
Researcher at University of Maryland, Baltimore
Publications - 472
Citations - 90624
Jack M. Guralnik is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Population & Anemia. The author has an hindex of 148, co-authored 453 publications receiving 83701 citations. Previous affiliations of Jack M. Guralnik include National Institutes of Health & University of Florida.
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Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons
Michelangela Barbieri,L. Ferrucci,Emilia Ragno,Annamaria Corsi,Stefania Bandinelli,Massimiliano Bonafè,Fabiola Olivieri,Simona Giovagnetti,Claudio Franceschi,Jack M. Guralnik,Giuseppe Paolisso +10 more
TL;DR: IL-6, IGF-I, and their interaction were significant predictors of handgrip and muscle power in a population-based sample of 526 persons with a wide age range and may explain why IL-6 is a strong risk factor for disability.
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Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study
Matteo Cesari,Marco Pahor,Benedetta Bartali,Antonio Cherubini,Brenda W.J.H. Penninx,G. Rhys Williams,Hal H. Atkinson,Antonio Martin,Jack M. Guralnik,Luigi Ferrucci +9 more
TL;DR: Higher dietary intakes of most antioxidants, especially vitamin C, appear to be associated with higher skeletal muscular strength in elderly persons, and plasma antioxidant concentrations correlate positively with physical performance and strength.
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Reliability and sensitivity to change assessed for a summary measure of lower body function: results from the Women's Health and Aging Study.
TL;DR: The results show that the summary performance measure has excellent reliability and is highly sensitive to change.
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Insulin-Like Growth Factor I and Interleukin-6 Contribute Synergistically to Disability and Mortality in Older Women
TL;DR: The combination of low IGF-I and high IL-6 levels confers a high risk for progressive disability and death in older women, suggesting an aggregate effect of dysregulation in endocrine and immune systems.
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Motivators and Barriers to Exercise in an Older Community-Dwelling Population
TL;DR: There is a need for individualized and comprehensive approaches to the presentation of exercise programs that will address both physical pain and depressed affect and explain the importance of exercise even in the presence of health problems.