J
Jack M. Guralnik
Researcher at University of Maryland, Baltimore
Publications - 472
Citations - 90624
Jack M. Guralnik is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Population & Anemia. The author has an hindex of 148, co-authored 453 publications receiving 83701 citations. Previous affiliations of Jack M. Guralnik include National Institutes of Health & University of Florida.
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Journal ArticleDOI
Lower Extremity Strength and Power Are Associated With 400-Meter Walk Time in Older Adults: The InCHIANTI Study
Anthony P. Marsh,Michael E. Miller,Aaron M. Saikin,W. Jack Rejeski,Nan Hu,Fulvio Lauretani,Stefania Bandinelli,Jack M. Guralnik,Luigi Ferrucci +8 more
TL;DR: Lower extremity muscle strength and power are both important predictors of the 400-meter walk time, although curvilinear relationships existed, the data do not indicate a clear threshold for either strength or power above which the performance in the400- meter walk test plateaus.
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Decline in Functional Performance Predicts Later Increased Mobility Loss and Mortality in Peripheral Arterial Disease
Mary M. McDermott,Kiang Liu,Luigi Ferrucci,Lu Tian,Jack M. Guralnik,Yihua Liao,Michael H. Criqui +6 more
TL;DR: People with PAD with declining functional performance are at increased risk for later mobility loss and mortality, and greater declines in fastest-paced 4-m walking velocity were associated with higher mobility loss.
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Relationship of an advanced glycation end product, plasma carboxymethyl-lysine, with slow walking speed in older adults: the InCHIANTI study.
TL;DR: In older community-dwelling adults, elevated plasma CML is independently associated with slow walking speed, and in older community the relationship between a plasma AGE, carboxymethyl-lysine (CML), and slowwalking speed in older adults is characterized.
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The ankle brachial index independently predicts walking velocity and walking endurance in peripheral arterial disease.
Mary M. McDermott,Kiang Liu,Jack M. Guralnik,Shruti H. Mehta,Michael H. Criqui,Gary J. Martin,Philip Greenland +6 more
TL;DR: The relationships between lower extremity peripheral arterial disease (PAD), PAD severity, and PAD‐related symptoms with walking velocity and endurance among men and women aged 55 and older are reported.
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Effects of the diabetes linked TCF7L2 polymorphism in a representative older population
David Melzer,Anna Murray,Alison J. Hurst,Michael N. Weedon,Stefania Bandinelli,Anna Maria Corsi,Luigi Ferrucci,Guiseppe Paolisso,Jack M. Guralnik,Timothy M. Frayling +9 more
TL;DR: The TCF7L2 rs7903146 polymorphism is associated with lower insulin levels, smaller waist circumference, and lower risk lipid profiles in the general elderly population, and may have implications for developing treatment approaches tailored by genotype.