J
Jacky G. Goetz
Researcher at University of Strasbourg
Publications - 103
Citations - 5513
Jacky G. Goetz is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Circulating tumor cell & Metastasis. The author has an hindex of 30, co-authored 93 publications receiving 4211 citations. Previous affiliations of Jacky G. Goetz include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Journal ArticleDOI
Fibrillar cellular fibronectin supports efficient platelet aggregation and procoagulant activity.
Eric Maurer,Mathieu Schaff,Nicolas Receveur,Catherine Bourdon,Luc Mercier,Bernhard Nieswandt,Christophe Dubois,Martine Jandrot-Perrus,Jacky G. Goetz,François Lanza,Christian Gachet,Pierre Mangin +11 more
TL;DR: Fibrillar cellular fibronectin is a strong thrombogenic surface which supports efficient platelet adhesion, activation, aggregation and procoagulant activity through the interplay of a series of receptors including integrins α5β1 and αIIbβ3, the GPIb-V-IX complex, GPVI and Toll-like receptor 4.
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Nanocomposite Polymer Scaffolds Responding under External Stimuli for Drug Delivery and Tissue Engineering Applications
Damien Mertz,Sébastien Harlepp,Jacky G. Goetz,Dominique Begin,Guy Schlatter,Sylvie Begin-Colin,Anne Hébraud +6 more
TL;DR: The blossoming development of nanomaterials and polymer science has opened the way toward new biocompatible scaffolds responding remotely to external stimuli (magnetic field, light, electric field) that hold great promises to achieve a controlled delivery of therapeutics for various diseases.
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The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is selectively recognized by the 3F3A antibody within a subdomain of the endoplasmic reticulum.
Marilyn Registre,Jacky G. Goetz,Pascal St. Pierre,Hao Pang,Monique Lagacé,Michel Bouvier,Phuong U. Le,Ivan R. Nabi +7 more
TL;DR: Data indicate that 3F3A antibody binding is highly specific for a subpopulation of expressed AMFR localized to a subdomain of the ER.
Journal ArticleDOI
Hemodynamic forces can be accurately measured in vivo with optical tweezers.
TL;DR: The power of optical tweezing is demonstrated in measuring low-range hemodynamic forces in vivo and, thereby, offer an unprecedented tool for both cell and developmental biology.
Journal ArticleDOI
Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide
Laurent Jacob,Paul Sawma,Norbert Garnier,Lionel A.T. Meyer,Justine Fritz,Thomas Hussenet,Caroline Spenlé,Jacky G. Goetz,Julien Vermot,Aurore Fernandez,Nadège Baumlin,Samia Aci-Sèche,Gertraud Orend,G. Roussel,Gérard Crémel,Monique Genest,Pierre Hubert,Dominique Bagnard +17 more
TL;DR: It is found that this Plexin-A1 peptidic antagonist exhibits anti-tumor activity in vivo on different human glioblastoma models including glioma cancer stem cells.