J
Jacob H. Rand
Researcher at Albert Einstein College of Medicine
Publications - 109
Citations - 7130
Jacob H. Rand is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Antiphospholipid syndrome & Annexin A5. The author has an hindex of 41, co-authored 108 publications receiving 6766 citations. Previous affiliations of Jacob H. Rand include Icahn School of Medicine at Mount Sinai & Montefiore Medical Center.
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Journal ArticleDOI
Update of the guidelines for lupus anticoagulant detection
Vittorio Pengo,Armando Tripodi,Guido Reber,Jacob H. Rand,Thomas L. Ortel,Monica Galli,de Peter Groot +6 more
TL;DR: Modalities for blood collection and processing are fully delineated and the choice of tests is limited to dRVVT and a sensitive aPTT and the interpretation of the results in general and in particular situations is reported.
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Pregnancy Loss in the Antiphospholipid-Antibody Syndrome — A Possible Thrombogenic Mechanism
Jacob H. Rand,Xiao-Xuan Wu,Harry A.M. Andree,Charles J. Lockwood,Seth Guller,Jonathan Scher,Peter C. Harpel +6 more
TL;DR: Antiphospholipid antibodies reduce the levels of annexin V and accelerate the coagulation of plasma on cultured trophoblasts and endothelial cells and how they affect the procoagulant activity of these cells is studied.
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Acquired von Willebrand syndrome: data from an international registry.
Augusto B. Federici,Jacob H. Rand,Paolo Bucciarelli,U. Budde,P. J. J. Van Genderen,Hiroshi Mohri,Dominique Meyer,Francesco Rodeghiero,J E Sadler +8 more
TL;DR: It appears that AvWS is especially frequent in lympho- or myeloproliferative and cardiovascular diseases and should be suspected and searched with the appropriate laboratory tests especially when excessive bleeding occurs in patients with these disorders.
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The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study.
B. de Laat,Vittorio Pengo,Ingrid Pabinger,Jacek Musiał,Alexandre E. Voskuyl,Irene E. M. Bultink,Amelia Ruffatti,Blaž Rozman,T. Kveder,P. De Moerloose,Françoise Boehlen,Jacob H. Rand,Z. Ulcova-Gallova,Koen Mertens,P. G. De Groot +14 more
TL;DR: In this multicenter study, the detection of IgG antibodies that are directed against domain I of beta2GPI proved to be more strongly associated with thrombosis and obstetric complications than those detected using the standard anti‐beta2G PI antibody assay.
Journal ArticleDOI
How I treat the acquired von Willebrand syndrome.
TL;DR: The management of AVWS is reviewed with an overview on the currently available evidence and additional considerations for typical treatment situations, including treatment options including desmopressin, VWF-containing concentrates, intravenous immunoglobulin, plasmapheresis or recombinant factor VIIa.