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Jacobo de la Cuesta-Zuluaga

Researcher at Max Planck Society

Publications -  21
Citations -  1362

Jacobo de la Cuesta-Zuluaga is an academic researcher from Max Planck Society. The author has contributed to research in topics: Microbiome & Gut flora. The author has an hindex of 11, co-authored 19 publications receiving 814 citations. Previous affiliations of Jacobo de la Cuesta-Zuluaga include University of Antioquia.

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Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid-Producing Microbiota in the Gut.

TL;DR: The hypothesis that metformin shifts gut microbiota composition through the enrichment of mucin-degrading A. muciniphila as well as several SCFA-producing microbiota is supported.
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Higher Fecal Short-Chain Fatty Acid Levels Are Associated with Gut Microbiome Dysbiosis, Obesity, Hypertension and Cardiometabolic Disease Risk Factors

TL;DR: Higher SCFA excretion was associated with evidence of gut dysbiosis, gut permeability, excess adiposity, and cardiometabolic risk factors, and studies assessing both fecal and circulating SCFAs are needed.
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Age- and Sex-Dependent Patterns of Gut Microbial Diversity in Human Adults.

TL;DR: Large-scale analyses of the relationship of age and sex to gut bacterial diversity in adult cohorts from four geographic regions found sex-dependent differences that were more pronounced in younger adults than in middle-aged adults, with women having higher alpha diversity than men.
Posted ContentDOI

Age and sex-dependent patterns of gut microbial diversity in human adults

TL;DR: In three of the four cohorts, a strong positive association between age and alpha diversity in young adults that plateaued after age 40 was observed, and women had higher alpha diversity than men in the US and UK cohort, with a reduced difference above age 40.
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Gut microbiota is associated with obesity and cardiometabolic disease in a population in the midst of Westernization.

TL;DR: In insights into the evolution of the gut microbiota, the importance of this community to human health is underscored, and the growth of specific microbial consortia could help ameliorating physiological conditions associated with Western lifestyles.