J
Jacobus F.A. Jansen
Researcher at Maastricht University
Publications - 206
Citations - 6865
Jacobus F.A. Jansen is an academic researcher from Maastricht University. The author has contributed to research in topics: Medicine & Epilepsy. The author has an hindex of 41, co-authored 162 publications receiving 5192 citations. Previous affiliations of Jacobus F.A. Jansen include Johns Hopkins University School of Medicine & Radboud University Nijmegen.
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Journal ArticleDOI
1H MR Spectroscopy of the Brain: Absolute Quantification of Metabolites
TL;DR: Important methodological aspects in an absolute quantification strategy are addressed, including radiofrequency coil properties, calibration procedures, spectral fitting methods, cerebrospinal fluid content correction, macromolecule suppression, and spectral editing.
Journal ArticleDOI
Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease
Harm J. van de Haar,Saartje Burgmans,Jacobus F.A. Jansen,Matthias J.P. van Osch,Mark A. van Buchem,Majon Muller,Paul A. M. Hofman,Frans R.J. Verhey,Walter H. Backes +8 more
TL;DR: The results of this study showed global BBB leakage in patients with early AD that is associated with cognitive decline that may be part of a cascade of pathologic events that eventually lead to cognitive decline and dementia.
Journal ArticleDOI
Cerebral blood flow, blood supply, and cognition in Type 2 Diabetes Mellitus
Jacobus F.A. Jansen,Frank C.G. van Bussel,Harm J. van de Haar,Matthias J.P. van Osch,Paul A. M. Hofman,Martin P.J. van Boxtel,Robert J. van Oostenbrugge,Miranda T. Schram,Coen D.A. Stehouwer,Joachim E. Wildberger,Walter H. Backes +10 more
TL;DR: A novel method that tallies total ‘distributed deviating voxels’ demonstrates T2DM-associated hypoperfusion in the subcortical GM, not associated with cognitive performance and whether a vascular mechanism underlies cognitive decrements remains inconclusive.
Journal ArticleDOI
Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease (vol 281, pg 527, 2016)
Harm J. van de Haar,Saartje Burgmans,Jacobus F.A. Jansen,Matthias J.P. van Osch,Mark A. van Buchem,Majon Muller,Paul Hofman,Frans R.J. Verhey,Walter H. Backes +8 more
Journal ArticleDOI
Functional connectivity of dissociation in patients with psychogenic non-epileptic seizures
Sylvie J.M. van der Kruijs,Nynke M.G. Bodde,Maarten J. Vaessen,R.H.C. Lazeron,Kristl Vonck,Paul Boon,Paul A. M. Hofman,Walter H. Backes,Albert P. Aldenkamp,Jacobus F.A. Jansen +9 more
TL;DR: In this article, the authors investigated whether PNES patients differ from healthy controls in their resting-state functional connectivity characteristics and whether these connections are associated with the tendency to dissociate.