J
Jacqueline Gruest
Researcher at Pasteur Institute
Publications - 31
Citations - 10483
Jacqueline Gruest is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Virus & Retrovirus. The author has an hindex of 12, co-authored 31 publications receiving 10257 citations.
Papers
More filters
Journal ArticleDOI
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).
Françoise Barré-Sinoussi,J. C. Chermann,Félix A. Rey,Marie-Thérèse Nugeyre,S. Chamaret,Jacqueline Gruest,Charles Dauguet,Claudine Axler-Blin,F. Vézinet-Brun,Christine Rouzioux,Willy Rozenbaum,Luc Montagnier +11 more
TL;DR: From these studies it is concluded that this virus as well as the previous HTLV isolates belong to a general family of T-lymphotropic retroviruses that are horizontally transmitted in humans and may be involved in several pathological syndromes, including AIDS.
Journal ArticleDOI
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
David Klatzmann,Eric Champagne,S. Chamaret,Jacqueline Gruest,Denise Guetard,Thierry Hercend,Jean Claude Gluckman,Luc Montagnier +7 more
TL;DR: Preincubation of T4+ lymphocytes with three individual monoclonal antibodies directed at the T4 glycoprotein blocked cell infection by LAV, strongly support the view that a surface molecule directly involved in cellular functions acts as, or is related to, the receptor for a human retrovirus.
Journal Article
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). 1983.
Barre-Sinoussi F,J. C. Chermann,Félix A. Rey,M T Nugeyre,Chamaret S,Jacqueline Gruest,Charles Dauguet,Claudine Axler-Blin,F. Vézinet-Brun,Christine Rouzioux,Willy Rozenbaum,Luc Montagnier +11 more
TL;DR: It is concluded that this virus as the previous HTVL isolate belong to a general family of T-lymphotropic retroviruses that are horizontally transmitted in human and may be involved in several pathological syndromes, including AIDS.
Journal ArticleDOI
Adaptation of Lymphadenopathy Associated Virus (LAV) to Replication in EBV-Transformed B Lymphoblastoid Cell Lines
Luc Montagnier,Jacqueline Gruest,S. Chamaret,Charles Dauguet,C. Axler,Denise Guetard,Marie-Thérèse Nugeyre,Françoise Barré-Sinoussi,J.C. Chermann,J. B. Brunet,David Klatzmann,Jean Claude Gluckman +11 more
TL;DR: A strain of lymphadenopathy associated retrovirus passaged in vitro was used to infect a lymphoblastoid cell line obtained by transformation with Epstein-Barr virus of B lymphocytes from a healthy donor, and this adapted strain retained the biochemical, ultrastructural, and antigenic characteristics of the original strain.
Patent
Human Immunodeficiency Virus (HIV) associated with Acquired Immunual Deficiency Syndrome (AIDS), a diagnostic method for aids and pre-aids, and a kit therefor
Luc Montagnier,Jean-Claude Chermann,Françoise Barré-Sinoussi,Francoise Brun-Vezinet,Christine Rouzioux,Willy Rozenbaum,Charles Dauguet,Jacqueline Gruest,Marie-Thérèse Nugeyre,Francoise Rey,Claudine Axler-Blin,Solange Chamaret,Robert C. Gallo,Mikulas Popovic,Mangalasseril G. Sarngadharan +14 more
TL;DR: In this article, a kit for in vitro assay of Lymphadenopathy Syndrome (LAS) or AIDS is provided, where immunological reaction is used to detect antibodies that specifically bind to antigenic sites of the retrovirus in samples of body fluids from patients with AIDS or risk of AIDS.