W
Willy Rozenbaum
Researcher at Centre national de la recherche scientifique
Publications - 108
Citations - 11476
Willy Rozenbaum is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Viral load & Didanosine. The author has an hindex of 35, co-authored 104 publications receiving 11173 citations.
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Journal ArticleDOI
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).
Françoise Barré-Sinoussi,J. C. Chermann,Félix A. Rey,Marie-Thérèse Nugeyre,S. Chamaret,Jacqueline Gruest,Charles Dauguet,Claudine Axler-Blin,F. Vézinet-Brun,Christine Rouzioux,Willy Rozenbaum,Luc Montagnier +11 more
TL;DR: From these studies it is concluded that this virus as well as the previous HTLV isolates belong to a general family of T-lymphotropic retroviruses that are horizontally transmitted in humans and may be involved in several pathological syndromes, including AIDS.
Journal Article
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). 1983.
Barre-Sinoussi F,J. C. Chermann,Félix A. Rey,M T Nugeyre,Chamaret S,Jacqueline Gruest,Charles Dauguet,Claudine Axler-Blin,F. Vézinet-Brun,Christine Rouzioux,Willy Rozenbaum,Luc Montagnier +11 more
TL;DR: It is concluded that this virus as the previous HTVL isolate belong to a general family of T-lymphotropic retroviruses that are horizontally transmitted in human and may be involved in several pathological syndromes, including AIDS.
Journal ArticleDOI
Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance
Jean Philippe Bastard,Martine Caron,Hubert Vidal,Véronique Jan,Martine Auclair,Corinne Vigouroux,J Luboinski,Martine Laville,Mustapha Maachi,Pierre Marie Girard,Willy Rozenbaum,Philippe Levan,Jacqueline Capeau +12 more
TL;DR: The altered differentiation status of peripheral adipocytes in HIV-1-infected patients with antiretroviral-induced lipoatrophy is associated with greatly reduced SREBP1c expression, which may lead to metabolic alterations such as insulin resistance.
Journal ArticleDOI
Factors related to lipodystrophy and metabolic alterations in patients with human immunodeficiency virus infection receiving highly active antiretroviral therapy.
Marianne Savès,Raffi François,Capeau Jacqueline,Willy Rozenbaum,Jean-Marie Ragnaud,Christian Perronne,Arnaud Basdevant,Catherine Leport,Chêne Geneviève +8 more
TL;DR: Age was significantly associated with different phenotypes of lipodystrophy and metabolic alterations, but body-mass index, CD4(+) cell count, and type of nucleoside reverse-transcriptase inhibitor or PI received were not constantly associated with these changes.
Journal ArticleDOI
Antimoniotungstate (HPA 23) treatment of three patients with AIDS and one with prodrome.
Willy Rozenbaum,Dominique Dormont,Bruno Spire,Etienne Vilmer,M Gentilini,Claude Griscelli,Luc Montagnier,Françoise Barré-Sinoussi,J.C. Chermann +8 more
TL;DR: Assays of infectivity showed that HPA 23 was inhibiting virus replication without killing virus infected cells, the first demonstration of inhibition of the growth of LAV in AIDS patients, and it remains to be established whether antiviral drugs can cure AIDS.