Jacques Diebold

TL;DR: The experience of developing the WHO Classification has produced a new and exciting degree of cooperation and communication between oncologists and pathologists from around the world, which should facilitate progress in the understanding and treatment of hematologic malignancies.

TL;DR: The World Health Organization classification of hematologic malignancies, including lymphoid, myeloid, histiocytic, and mast cell neoplasms, has produced a new and exciting degree of cooperation and communication between oncologists and pathologists from around the world, which should facilitate progress in the understanding and treatment ofhematologicmalignancies.

TL;DR: Data suggest that expression of survivin in embryonic and fetal development may contribute to tissue homeostasis and differentiation independently of bcl-2, and Aberrations of this developmental pathway may result in prominent re-expression of Survivin in neoplasia and abnormally prolonged cell viability.

TL;DR: Although the poor prognosis of non-ALCL PTCL could be due in part to the presence of adverse prognostic factors at diagnosis, this study shows that the T-cell phenotype is an independent significant factor, which should be incorporated into the definition of prognostic groups.

TL;DR: B cl-2 protein expression, as demonstrated in routinely paraffin-embedded tissue, appears to be predictive of poor DFS, in agreement with the role of bcl-2 in chemotherapy-induced apoptosis.