J
Jae-Ha Ryu
Researcher at Sookmyung Women's University
Publications - 41
Citations - 2066
Jae-Ha Ryu is an academic researcher from Sookmyung Women's University. The author has contributed to research in topics: Nitric oxide synthase & Nitric oxide. The author has an hindex of 22, co-authored 41 publications receiving 1902 citations. Previous affiliations of Jae-Ha Ryu include Rutgers University.
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Modulation of arachidonic acid metabolism by curcumin and related β-diketone derivatives: effects on cytosolic phospholipase A2, cyclooxygenases and 5-lipoxygenase
Jungil Hong,Mousumi Bose,Jihyeung Ju,Jae-Ha Ryu,Xiaoxin Chen,Shengmin Sang,Mao Jung Lee,Chung S. Yang +7 more
TL;DR: Curcumin affects arachidonic acid metabolism by blocking the phosphorylation of cPLA(2), decreasing the expression of COX-2 and inhibiting the catalytic activities of 5-LOX, which may contribute to the anti-inflammatory and anticarcinogenic actions of curcumin and its analogs.
Journal Article
Stability, Cellular Uptake, Biotransformation, and Efflux of Tea Polyphenol (−)-Epigallocatechin-3-Gallate in HT-29 Human Colon Adenocarcinoma Cells
TL;DR: The results suggest that EGCG is metabolized in the cell and that the metabolites are pumped out by MRPs, and suggests the need for careful interpretation of related results on the biological activities of E GCG.
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Effects of bisphenol A on breast cancer and its risk factors.
TL;DR: Considering interactions between BPA exposure and risks of breast cancer, it is suggested further enlarged biomonitoring studies of BPA to provide effective prevention against breast cancer.
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Inhibitory activity of plant extracts on nitric oxide synthesis in LPS-activated macrophages.
TL;DR: These plants are promising candidates for the study of the activity‐guided purification of active compounds and would be useful for the treatment of inflammatory diseases and endotoxemia accompanying overproduction of NO.
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Curcumin downregulates the constitutive activity of NF-κB and induces apoptosis in novel mouse melanoma cells
Yarí E. Marín,Brian A. Wall,Su Wang,Jin Namkoong,Jeffrey J. Martino,Junghan Suh,Junghan Suh,Hwa Jin Lee,Arnold B. Rabson,Chung S. Yang,Suzie Chen,Jae-Ha Ryu +11 more
TL;DR: It is concluded that curcumin, a natural and safe compound, inhibits NF-κB activity and the expression of its downstream target genes, and also selectively induces apoptosis of melanoma cells but not normal melanocytes.