Jae-Han Jeon

TL;DR: To facilitate the understanding of vascular calcification, across any number of bioscientific disciplines, this review of a detailed updated molecular mechanism of VC encompasses a vascular smooth muscle phenotypic of osteogenic differentiation, and multiple signaling pathways of VC induction, including the roles of inflammation and cellular microorganelle genesis.

TL;DR: The roles of PDC in diverse tissues and how regulation of its activity is affected in various metabolic disorders are summarized.

TL;DR: Both diets led to reductions in HbA1c levels; however, glycemic control was better with the vegan diet than with the conventional diet, and the dietary guidelines for patients with T2D should include a vegan diet for the better management and treatment.

TL;DR: It is demonstrated that PDK4 interacts with and stabilizes the IP3R1-GRP75-VDAC1 complex at the MAM interface and that forced formation and stabilization of MAMs with synthetic ER–mitochondria linker prevented the beneficial effects ofPDK4 deficiency on insulin signaling.

TL;DR: The findings imply that COVID-19 patients with DM, especially if elderly, require special attention and prompt intensive care.