J
Jaewon Choi
Researcher at Samsung Medical Center
Publications - 9
Citations - 448
Jaewon Choi is an academic researcher from Samsung Medical Center. The author has contributed to research in topics: Mesenchymal stem cell & Inhibitor of apoptosis. The author has an hindex of 8, co-authored 8 publications receiving 430 citations.
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Journal ArticleDOI
Gene expression profile of cytokine and growth factor during differentiation of bone marrow-derived mesenchymal stem cell.
Dong Hyun Kim,Keon Hee Yoo,Kyung-Suk Choi,Jaewon Choi,Sang Yun Choi,Sung-Eun Yang,Yoon-Sun Yang,Ho Joon Im,Kye Hyun Kim,Hye Lim Jung,Ki Woong Sung,Hong Hoe Koo +11 more
TL;DR: Using RT-PCR analysis, the expression levels of cytokines and growth factors from MSCs and their differentiated cell types, including osteoblasts, adipocytes and endothelial cells are examined to help determine future clinical applications of MSCS and their derivatives for cell therapy.
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Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia
Jaewon Choi,Yu Kyeong Hwang,Ki Woong Sung,Soo Hyun Lee,Keon Hee Yoo,Hye Lim Jung,Hong Hoe Koo,Hee Jin Kim,Hyong Jin Kang,Hee Young Shin,Hyo Seop Ahn +10 more
TL;DR: It is suggested that Livin expression is a novel prognostic marker in childhood ALL and thus needs to be incorporated into the patient stratification and treatment protocols.
Journal ArticleDOI
Overexpression of Apollon, an Antiapoptotic Protein, Is Associated with Poor Prognosis in Childhood De novo Acute Myeloid Leukemia
Ki Woong Sung,Jaewon Choi,Yu Kyeong Hwang,Sang Jin Lee,Hee Jin Kim,Soo Hyun Lee,Keon Hee Yoo,Hye Lim Jung,Hong Hoe Koo +8 more
TL;DR: This is the first study demonstrating the prognostic implication of theApollon expression in human cancers, indicating that Apollon overexpression may be used as a poor prognostic marker in childhood acute myeloid leukemia through validation by further studies.
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Cotransplanted bone marrow derived mesenchymal stem cells (MSC) enhanced engraftment of hematopoietic stem cells in a MSC-dose dependent manner in NOD/SCID mice.
Dong Hyun Kim,Dong Hyun Kim,Keon Hee Yoo,Young Sook Yim,Jaewon Choi,Soo Hyun Lee,Hye Lim Jung,Ki Woong Sung,Sung-Eun Yang,Won Il Oh,Yoon Sun Yang,Sang Hee Kim,Sang Yun Choi,Hong Hoe Koo +13 more
TL;DR: The results suggest that the optimal ratio of HSCs and MSCs for cotransplantation might be in the range of 1:8-1:16; whereas, an excessive dose of M SCs might decrease engraftment efficiency.
Journal ArticleDOI
Overexpression of X-linked Inhibitor of Apoptosis Protein (XIAP) is an Independent Unfavorable Prognostic Factor in Childhood de Novo Acute Myeloid Leukemia
Ki Woong Sung,Jaewon Choi,Yu Kyeong Hwang,Sang Jin Lee,Hee Jin Kim,Ju Youn Kim,Eun Joo Cho,Keon Hee Yoo,Hong Hoe Koo +8 more
TL;DR: In 53 children with de novo AML, the level of XIAP expression was determined by using quantitative reverse transcriptase-polymerase chain reaction and was analyzed with respect to the clinical characteristics at diagnosis and treatment outcomes and revealed that XIAP overexpression was an independent unfavorable prognostic factor for relapse-free survival.