K
Keon Hee Yoo
Researcher at Samsung Medical Center
Publications - 206
Citations - 3362
Keon Hee Yoo is an academic researcher from Samsung Medical Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 26, co-authored 186 publications receiving 2797 citations. Previous affiliations of Keon Hee Yoo include Sungkyunkwan University.
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Journal ArticleDOI
Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues
Keon Hee Yoo,In Keun Jang,Myoung Woo Lee,Hyo Eun Kim,Mal Sook Yang,Young-Woo Eom,Jong Eun Lee,Young-Jin Kim,Seong Kyu Yang,Hye Lim Jung,Ki Woong Sung,Cheol Woo Kim,Hong Hoe Koo +12 more
TL;DR: Findings suggest that MSCs derived from AT, CB, or WJ could be substituted for BM-MSCs for treatment of allogeneic conflicts.
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Gene expression profile of cytokine and growth factor during differentiation of bone marrow-derived mesenchymal stem cell.
Dong Hyun Kim,Keon Hee Yoo,Kyung-Suk Choi,Jaewon Choi,Sang Yun Choi,Sung-Eun Yang,Yoon-Sun Yang,Ho Joon Im,Kye Hyun Kim,Hye Lim Jung,Ki Woong Sung,Hong Hoe Koo +11 more
TL;DR: Using RT-PCR analysis, the expression levels of cytokines and growth factors from MSCs and their differentiated cell types, including osteoblasts, adipocytes and endothelial cells are examined to help determine future clinical applications of MSCS and their derivatives for cell therapy.
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Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-γ
Dae Seong Kim,In Keun Jang,Myoung Woo Lee,Young Jong Ko,Doo-Hoon Lee,Ji Won Lee,Ki Woong Sung,Hong Hoe Koo,Hong Hoe Koo,Keon Hee Yoo,Keon Hee Yoo +10 more
TL;DR: Infusion of MSCs primed with IFN-γ significantly reduced the symptoms of graft-versus-host disease (GVHD) in NOD-SCID mice, thereby increasing survival rate when compared with naïve MSC-infused mice.
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Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia
Jaewon Choi,Yu Kyeong Hwang,Ki Woong Sung,Soo Hyun Lee,Keon Hee Yoo,Hye Lim Jung,Hong Hoe Koo,Hee Jin Kim,Hyong Jin Kang,Hee Young Shin,Hyo Seop Ahn +10 more
TL;DR: It is suggested that Livin expression is a novel prognostic marker in childhood ALL and thus needs to be incorporated into the patient stratification and treatment protocols.
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Mesenchymal stem cells in suppression or progression of hematologic malignancy: current status and challenges
Myoung Woo Lee,Somi Ryu,Dae Seong Kim,Ji Won Lee,Ki Woong Sung,Hong Hoe Koo,Hong Hoe Koo,Keon Hee Yoo,Keon Hee Yoo +8 more
TL;DR: It is necessary to take extreme care while developing MSC-based cell therapies in order to boost anticancer properties while eliminating tumor-favoring effects, and research on the therapeutic applications of MSCs must consider that they exert both antitumorigenic and protum origenic effects on hematologic malignancies.