J
Jakob Matschke
Researcher at University of Hamburg
Publications - 157
Citations - 4776
Jakob Matschke is an academic researcher from University of Hamburg. The author has contributed to research in topics: Medicine & Glioma. The author has an hindex of 28, co-authored 143 publications receiving 3284 citations. Previous affiliations of Jakob Matschke include University of Zurich & Eppendorf (Germany).
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Journal ArticleDOI
Neuropathology of patients with COVID-19 in Germany: a post-mortem case series.
Jakob Matschke,Marc Lütgehetmann,Christian Hagel,Jan Sperhake,Ann Sophie Schröder,Carolin Edler,Herbert Mushumba,Antonia Fitzek,Lena Allweiss,Maura Dandri,Matthias Dottermusch,Axel Heinemann,Susanne Pfefferle,Marius Schwabenland,Daniel Sumner Magruder,Stefan Bonn,Stefan Bonn,Marco Prinz,Christian Gerloff,Klaus Püschel,Susanne Krasemann,Martin Aepfelbacher,Markus Glatzel +22 more
TL;DR: In general, neuropathological changes in patients with COVID-19 seem to be mild, with pronounced neuroinflammatory changes in the brainstem being the most common finding, and there was no evidence for CNS damage directly caused by SARS-CoV-2.
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Hematogenous dissemination of glioblastoma multiforme
Carolin Müller,Johannes Holtschmidt,Martina Auer,Ellen Heitzer,Katrin Lamszus,Alexander Schulte,Jakob Matschke,Sabine Langer-Freitag,Christin Gasch,Malgorzata Stoupiec,Oliver Mauermann,Sven Peine,Markus Glatzel,Michael R. Speicher,Jochen B. Geigl,Manfred Westphal,Klaus Pantel,Sabine Riethdorf +17 more
TL;DR: It is demonstrated that hematogenous GBM spread is an intrinsic feature of GBM biology and should not be allowed to serve as organ donors.
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Evidence for susceptibility to malignant hyperthermia in patients with exercise-induced rhabdomyolysis.
Frank Wappler,Marko Fiege,Markus Steinfath,Kamayni Agarwal,Jens Scholz,S. Singh,Jakob Matschke,Jochen Schulte am Esch +7 more
TL;DR: The authors recommend performing muscle biopsies for histologic examination and IVCT in patients with ER and screened for genetic abnormalities to shed light on the genetics of MH.
Journal Article
Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A.
Katrin Lamszus,Ulrike Ulbricht,Jakob Matschke,Marc A. Brockmann,Regina Fillbrandt,Manfred Westphal +5 more
TL;DR: The inhibition of tumor extract-induced endothelial chemotaxis by sVEGFR-1 suggests that sVEF-1 could be useful as an angiogenesis inhibitor in the specific context of human gliomas.
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Allelic Losses at 1p, 9q, 10q, 14q, and 22q in the Progression of Aggressive Meningiomas and Undifferentiated Meningeal Sarcomas
TL;DR: None of these genetic findings were present in the non-meningiomatous meningeal tumors, indicating that meningothelial cells have their own lineage-specific genetic pathways towards clinical malignancy.