J
James Bradac
Researcher at National Institutes of Health
Publications - 8
Citations - 1354
James Bradac is an academic researcher from National Institutes of Health. The author has contributed to research in topics: HIV vaccine & Serotype. The author has an hindex of 7, co-authored 8 publications receiving 1319 citations.
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Journal ArticleDOI
HIV-1 Nomenclature Proposal
David Robertson,Jon P. Anderson,James Bradac,Jean K. Carr,Brian T. Foley,RK Funkhouser,Feng Gao,Beatrice H. Hahn,Marcia L. Kalish,Carla Kuiken,Gerald H. Learn,Thomas Leitner,Francine E. McCutchan,Saladin Osmanov,Martine Peeters,Danuta Pieniazek,Mika Salminen,Paul M. Sharp,Steven M. Wolinsky,Bette T. Korber +19 more
TL;DR: A clear and consistent genetic classification of human immunodeficiency virus-type 1 (HIV-1) strains continues to be of great utility in epidemiological tracking of the AIDS pandemic and in vaccine design.
Journal ArticleDOI
Genetic variation of HIV type 1 in four World Health Organization-sponsored vaccine evaluation sites: generation of functional envelope (glycoprotein 160) clones representative of sequence subtypes A, B, C, and E. WHO Network for HIV Isolation and Characterization.
Feng Gao,Ling Yue,Stevenson Craig,Charlotte L. Thornton,David Robertson,Francince E. McCutchan,James Bradac,Paul M. Sharp,Beatrice H. Hahn +8 more
TL;DR: In this paper, the authors used PCR amplification, cloned, and sequenced gp120 and gp160 genes from 12 HIV-1 isolates collected in four WHO-sponsored vaccine evaluation sites (Brazil, Rwanda, Thailand, Uganda).
HIV-1 nomenclature proposal: a reference guide to HIV-1 classification.
David Robertson,Jon P. Anderson,James Bradac,Jean K. Carr,Brian T. Foley,RK Funkhouser,F Gao,BH Hahn,Marcia L. Kalish,Carla Kuiken,Gerald H. Learn,Thomas Leitner,Francince E. McCutchan,Saladin Osmanov,Martine Peeters,Danuta Pieniazek,Mika Salminen,Paul M. Sharp,Steven M. Wolinsky,Bette T. Korber +19 more
TL;DR: This study highlights the need to understand more fully the role of Epstein-Barr virus in the development of HIV/AIDS and its role in the immune response to chemotherapy and other infectious diseases.
Journal ArticleDOI
Human immunodeficiency virus type 1 neutralizing antibody serotyping using serum pools and an infectivity reduction assay
John R. Mascola,Mark K. Louder,Sonja R. Surman,Thomas C. VanCott,Xiao Fang Yu,James Bradac,Kevin R. Porter,Kenrad E. Nelson,Marc Girard,John G. McNeil,Francine E. McCutchan,Deborah L. Birx,Donald S. Burke +12 more
TL;DR: The data indicate that the phylogenetic classification of virus subtypes B and E corresponds to two distinct neutralization serotypes, which may be useful in defining the antigenic relationship among viruses from other clades.
Journal ArticleDOI
Neutralization of HIV-1
TL;DR: This workshop brought together researchers who are involved in the development, testing, and evaluation of HIV-1 prophylactic vaccines to discuss critically the different neutralization and binding assays that are currently used in the evaluation of immune sera.