J
James D. Eudy
Researcher at University of Nebraska Medical Center
Publications - 49
Citations - 2483
James D. Eudy is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Gene & Gene expression. The author has an hindex of 26, co-authored 44 publications receiving 2232 citations. Previous affiliations of James D. Eudy include Texas A&M University.
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Journal ArticleDOI
Mutation of a gene encoding a protein with extracellular matrix motifs in Usher syndrome type IIa
James D. Eudy,Michael D. Weston,Su Fang Yao,Denise M. Hoover,Heidi L. Rehm,Manling Ma-Edmonds,Denise Yan,Iqbal Ahmad,Jason J. Cheng,Carmen Ayuso,Cor W. R. J. Cremers,S. Davenport,Claes Möller,Catherine B. Talmadge,Kirk W. Beisel,Marta L. Tamayo,Cynthia C. Morton,Anand Swaroop,William J. Kimberling,Janos Sumegi +19 more
TL;DR: Three biologically important mutations in Usher syndrome type IIa patients were identified in a gene (USH2A) isolated from this critical region of human chromosome 1q41 that has laminin epidermal growth factor and fibronectin type III motifs.
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Genomic structure and identification of novel mutations in Usherin, the gene responsible for Usher syndrome type IIa.
Michael D. Weston,James D. Eudy,S. Fujita,Su Fang Yao,Shin-ichi Usami,Cor W. R. J. Cremers,J. Greenburg,Rajkumar Ramesar,Alessandro Martini,Claes Möller,Richard J.H. Smith,Janos Sumegi,William J. Kimberling +12 more
TL;DR: A mutation search of 57 independent USHIIa probands was performed with a combination of direct sequencing and heteroduplex analysis of PCR-amplified exons, and three new missense mutations were discovered; all were restricted to the previously unreported laminin domain VI region of Usherin.
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Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41.
James D. Eudy,SuFang Yao,Michael D. Weston,Manling Ma-Edmonds,Catherine B. Talmadge,Jason J. Cheng,William J. Kimberling,Janos Sumegi +7 more
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Induced Pluripotent Stem Cells Generate Both Retinal Ganglion Cells and Photoreceptors: Therapeutic Implications in Degenerative Changes in Glaucoma and Age‐Related Macular Degeneration
Sowmya Parameswaran,Sudha Balasubramanian,Norbert Babai,Fang Qiu,James D. Eudy,Wallace B. Thoreson,Iqbal Ahmad +6 more
TL;DR: It is demonstrated that mouse fibroblast induced pluripotent stem cells (iPSCs) represent a renewable and robust source ofretinal progenitors, capable of generating a wide range of retinal cell types that includes retinal ganglion cells (RGCs), cone, and rod photoreceptors.
Journal ArticleDOI
Identification and Characterization of the Human and Mouse SLC19A3 Gene: A Novel Member of the Reduced Folate Family of Micronutrient Transporter Genes
James D. Eudy,Ofer Spiegelstein,Robert Clinton Barber,Bogdan J. Wlodarczyk,Jeffrey Talbot,Richard H. Finnell +5 more
TL;DR: The identification of SLC19A3, a gene encoding a novel solute transporter, is described and established as a candidate gene for seizures in the DBA/2J mouse.