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James D. Neaton

Researcher at University of Minnesota

Publications -  352
Citations -  68183

James D. Neaton is an academic researcher from University of Minnesota. The author has contributed to research in topics: Risk factor & Blood pressure. The author has an hindex of 101, co-authored 331 publications receiving 64719 citations. Previous affiliations of James D. Neaton include University of Pittsburgh & Medical Research Council.

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Journal Article

Unrecognized myocardial infarction: experience in the Multiple Risk Factor Intervention Trial (MRFIT).

TL;DR: The primary purpose of the study was to see if lowering risk factors (diastolic blood pressure, blood cholesterol, and cigarette smoking) would result in a reduced incidence of death from coronary heart disease.
Journal Article

Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure

TL;DR: Whether losartan is superior to captopril in improving survival and is better tolerated and the ELITE II Losartan Heart Failure Survival Study is confirmed.
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Background and design of the new U.S. trial on diet and drug treatment of "mild" hypertension (TOMHS).

TL;DR: This trial is comparing the combined effects of diet treatment and 1 of 5 active drug regimens with diet treatment alone, for the long-term management of middle-aged adults with "mild" hypertension, with the ultimate aim to assess effects on morbidity and mortality.
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Unexpected effects of treating hypertension in men with electrocardiographic abnormalities: a critical analysis.

TL;DR: It is possible that the excess CHD mortality among MRFIT special intervention men with electrocardiographic abnormalities may have been caused by a combination of increased left ventricular mass in the presence of coronary atherosclerosis, and hypokalemia caused by good compliance with diuretic therapy and accentuated by stress-induced increases in circulating catecholamines.
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Lack of efficacy of Haemophilus b polysaccharide vaccine in Minnesota

TL;DR: It is indicated that vaccination with Haemophilus b polysaccharide vaccine had no effect in preventing H influenzae type b disease in Minnesota children.