J
James D. Neaton
Researcher at University of Minnesota
Publications - 352
Citations - 68183
James D. Neaton is an academic researcher from University of Minnesota. The author has contributed to research in topics: Risk factor & Blood pressure. The author has an hindex of 101, co-authored 331 publications receiving 64719 citations. Previous affiliations of James D. Neaton include University of Pittsburgh & Medical Research Council.
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Journal ArticleDOI
Considerations in choice of a clinical endpoint for AIDS clinical trials
James D. Neaton,Deborah Wentworth,Frank S. Rhame,Carlton Hogan,Donald I. Abrams,Lawrence Deyton +5 more
TL;DR: It is recommended that survival be the primary endpoint of antiretroviral trials, and that all opportunistic events experienced by patients, not just the first, be collected and summarized.
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Lipoprotein particles, insulin, adiponectin, C-reactive protein and risk of coronary heart disease among men with metabolic syndrome
TL;DR: Number of HDL particles, especially medium-sized HDL particles and WBC count were independent predictors of CHD death among men with MetSyn, and in multivariate models adjusting for smoking and LDL-C, medium HDL-P and W BC count remained independent predictor ofCHD death.
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Immunodeficiency and the risk of serious clinical endpoints in a well-studied cohort of treated HIV-infected patients
Amit C. Achhra,Janaki Amin,Matthew Law,Sean Emery,Jan Gerstoft,Fred M. Gordin,Michael J. Vjecha,James D. Neaton,David A. Cooper +8 more
TL;DR: Latest CD4+ cell count is the best predictor of serious endpoints andCD4+ slope independently predicts all-cause and non-AIDS deaths.
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Association between baseline risk factors, cigarette smoking, and CHD mortality after 10.5 years
TL;DR: Intervention on blood pressure and blood lipids is particularly important among cigarette smokers because of their increased risk of CHD death.
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The Multiple Risk Factor Intervention Trial (MRFIT)--importance then and now.
Jeremiah Stamler,James D. Neaton +1 more
TL;DR: The data of high precision show that the relationship between serum cholesterol and CHD is not a threshold one, with increased risk confined to the two highest quintiles, but rather is a continuously graded one that powerfully affects risk for the great majority of middle-aged American men.