James D. Simo Mpetga

TL;DR: Benzophenanthrine alkaloids 2 and 3 are the main antibacterial consituents of the roots of the plant and are a potential source of antimicrobial drugs to fight against MDR bacteria.

TL;DR: Three previously undescribed alkaloids displayed selective activities and Maculine B, the most active one among the newly described compounds, exhibited IC50 below 30 μM against CCRF-CEM leukemia and U87MG glioblastoma cells.

TL;DR: The antibacterial screening of the leaves of this plant, characterization of compounds 1 and 2 , and their antibacterial activity are reported for the first time.

TL;DR: Of the purified compounds, ericoside displayed moderate activity against the resistant Escherichia coli AG100 with a MIC of 64 μg/mL and was tested against ten Gram-negative bacteria including multidrug resistant clinical isolates using a broth microdilution method.

TL;DR: The structure elucidation is based on extensive 1D- and 2D-NMR, infrared, UV and MS experiments, and the structures of the known compounds were confirmed by comparison of their spectroscopic data with those of similar reported compounds in the literature.