James Golomb

TL;DR: The results of the present study indicate that hippocampal formation atrophy is associated with memory and cognitive impairments and further longitudinal and neuropathologic work is required to validate the relationship between hippocampal Formation atrophy and AD.

TL;DR: The findings strongly suggest that among persons with mild memory impairments, dilatation of the perihippocampal fissures is a useful radiologic marker for identifying the early features of Alzheimer disease.

TL;DR: It is concluded that HA is a common accompaniment of normal aging and is associated with mild memory impairment, and additional research is needed to determine whether HA constitutes a significant risk for future dementia.

TL;DR: Results indicate that motor impairment is an important aspect of cognitive decline in older adults and that motorlpsychomotor assessments may be comparably sensitive to traditional tests of cognitive function in identifying persons affected by the earliest stages of AD pathology.

TL;DR: Alzheimer's disease pathology is a common source of comorbidity in older patients with idiopathic NPH where it contributes to the clinical impairment associated with this disorder, but for patients accurately diagnosed with NPH, concomitant dementia severity does not strongly influence the clinical response to shunt surgery.