J
James John
Researcher at Sri Ramachandra University
Publications - 11
Citations - 176
James John is an academic researcher from Sri Ramachandra University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 5, co-authored 5 publications receiving 119 citations. Previous affiliations of James John include Central University, India.
Papers
More filters
Journal ArticleDOI
Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma.
TL;DR: The molecular mechanisms that come from other than HBV endemic places which can be innovative approaches to treat HCC are outlined.
Journal ArticleDOI
A novel mechanism of action of ketoconazole: inhibition of the NorA efflux pump system and biofilm formation in multidrug-resistant Staphylococcus aureus .
Rehab Mahmoud Abd El-Baky,Tim Sandle,James John,Gamal El Din A. Abuo-Rahma,Helal F Hetta,Helal F Hetta +5 more
TL;DR: The findings showed that the antifungal ketoconazole has no antibacterial activity but can potentiate the activity of the fluroquinolones against MDR S. aureus via inhibiting efflux pump and biofilm formation in vitro.
Journal ArticleDOI
Nanomedicine as a future therapeutic approach for Hepatitis C virus.
Noura H. Abd Ellah,Noura H. Abd Ellah,Hesham M. Tawfeek,Hesham M. Tawfeek,James John,Helal F Hetta,Helal F Hetta +6 more
TL;DR: The contribution of nanoparticles as a promising delivery system for HCV immunizing, diagnostic and therapeutic agents are discussed and there is a pressing need of new approaches for affordable and effective drug delivery systems using nanomedicine.
Journal ArticleDOI
Isolation and evaluation of cocktail phages for the control of multidrug-resistant Escherichia coli serotype O104: H4 and E. coli O157: H7 isolates causing diarrhea.
Doaa Safwat Mohamed,Eman Farouk Ahmed,Abobakr Mohamed Mahmoud,Rehab Mahmoud Abd El-Baky,James John +4 more
TL;DR: The tested phage cocktail showed a promising inhibitory action on E. coli, suggesting the possibility of its use as a biocontrol tool or as natural food preservatives for many food products.
Journal ArticleDOI
Assessment of Circulating miRNA-17 and miRNA-222 Expression Profiles as Non-Invasive Biomarkers in Egyptian Patients with Non-Small-Cell Lung Cancer.
Helal F Hetta,Helal F Hetta,Asmaa M Zahran,Reham I El-Mahdy,Emad Eldin Nabil,Hend M. Esmaeel,Ola A Elkady,Azza Elkady,Dina A Mohareb,Mohammed Mahmoud Mostafa,James John +10 more
TL;DR: MiRNA-17 and miRNA-222 can be considered as non-invasive biomarkers for detection of early lung carcinogenesis and metastasis in patients with NSCLC, hence providing a basis for the development of novel therapeutic approaches.