J
James M. Anderson
Researcher at Case Western Reserve University
Publications - 372
Citations - 24557
James M. Anderson is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Foreign-body giant cell & Macrophage fusion. The author has an hindex of 84, co-authored 372 publications receiving 23160 citations. Previous affiliations of James M. Anderson include University Hospitals of Cleveland & Mount Sinai St. Luke's and Mount Sinai Roosevelt.
Papers
More filters
Journal ArticleDOI
Biodegradation and biocompatibility of PLA and PLGA microspheres
TL;DR: This chapter is a critical review of biodegradation, biocompatibility and tissue/material interactions, and selected examples of PLA and PLGA microsphere controlled release systems, and emphasis is placed on polymer and microSphere characteristics which modulate the degradation behaviour and the foreign body reaction to the microspheres.
Journal ArticleDOI
Biocompatibility and biofouling of MEMS drug delivery devices
Gabriela Voskerician,Matthew S. Shive,Rebecca S. Shawgo,Horst A. von Recum,James M. Anderson,Michael J. Cima,Robert Langer +6 more
TL;DR: These analyses identified the MEMS component materials, gold, silicon nitride, silicon dioxide, SU-8(TM), and silicon as biocompatible, with gold and silicon showing reduced biofouling.
Journal ArticleDOI
Protein adsorption from human plasma is reduced on phospholipid polymers
TL;DR: It is concluded that the reduction of protein adsorption at the blood contacting surface of phospholipid polymers may result in the inhibition of thrombus formation.
Journal ArticleDOI
First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip
Robert Farra,Norman F. Sheppard,Laura McCabe,Robert M. Neer,James M. Anderson,John T. Santini,Michael J. Cima,Robert Langer +7 more
TL;DR: Although the implanted device needs additional engineering for higher number of doses, this controlled-release microchip developed by Farra and colleagues represents an important shift in drug delivery, wherein patients with chronic diseases, such as diabetes or osteoporosis, can adhere to their complex treatment plan without compromising quality of life.
Journal ArticleDOI
Multinucleated giant cells.
TL;DR: Recent studies directed toward developing a better understanding of the molecular and cellular biology basis of monocyte-derived multinucleated giant cell formation, function, and biologic activity are presented and HIV-1–infected T-lymphocyte syncytia and the significance of adhesion molecule/ligand interactions in the formation of these syncyts are described.