K
Kazuhiko Ishihara
Researcher at University of Tokyo
Publications - 726
Citations - 26844
Kazuhiko Ishihara is an academic researcher from University of Tokyo. The author has contributed to research in topics: Polymer & Protein adsorption. The author has an hindex of 77, co-authored 713 publications receiving 24795 citations. Previous affiliations of Kazuhiko Ishihara include Fukui University of Technology & Waseda University.
Papers
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Journal ArticleDOI
Why do phospholipid polymers reduce protein adsorption
Kazuhiko Ishihara,Hiroto Nomura,Hiroto Nomura,Takashi Mihara,Takashi Mihara,Kimio Kurita,Yasuhiko Iwasaki,Nobuo Nakabayashi +7 more
TL;DR: It is concluded that fewer proteins are adsorbed and their original conformation is not changed on polymer surfaces that possess a high free water fraction.
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Preparation of phospholipid polymers and their properties as polymer hydrogel membranes.
TL;DR: A methacrylate monomer having the phospholipid polar group, 2-methacryloyloxyethyl phosphorylcholine (MPC) was prepared by an improved method with good yield as mentioned in this paper.
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Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis
Toru Moro,Yoshio Takatori,Kazuhiko Ishihara,Tomohiro Konno,Yorinobu Takigawa,Tomiharu Matsushita,Ung Li Chung,Kozo Nakamura,Hiroshi Kawaguchi +8 more
TL;DR: This approach will make a major improvement in artificial joints by preventing periprosthetic osteolysis and being biologically inert by culture systems with respect to phagocytosis and resorptive cytokine secretion by macrophages.
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Protein adsorption from human plasma is reduced on phospholipid polymers
TL;DR: It is concluded that the reduction of protein adsorption at the blood contacting surface of phospholipid polymers may result in the inhibition of thrombus formation.
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Hemocompatibility of human whole blood on polymers with a phospholipid polar group and its mechanism.
TL;DR: It is concluded that the phospholipids adsorbed on poly(MPC-co-BMA) play the most important role in the nonthrombogenicity of the MPC copolymer.