J
James R. Henstock
Researcher at University of Liverpool
Publications - 23
Citations - 765
James R. Henstock is an academic researcher from University of Liverpool. The author has contributed to research in topics: Tissue engineering & Mechanotransduction. The author has an hindex of 12, co-authored 18 publications receiving 640 citations. Previous affiliations of James R. Henstock include Keele University.
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Journal ArticleDOI
Tissue engineered bone using select growth factors: A comprehensive review of animal studies and clinical translation studies in man.
D. Gothard,Emma L. Smith,Janos M. Kanczler,Hassan Rashidi,Omar Qutachi,James R. Henstock,Michael Rotherham,A.J. El Haj,Kevin M. Shakesheff,Richard O.C. Oreffo +9 more
TL;DR: Focus is drawn to the in vivo success of osteoinductive growth factors incorporated within material implants both in animals and humans, and identifies the unmet challenges within the skeletal regenerative area.
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Silicon: the evolution of its use in biomaterials.
TL;DR: This review discusses the current data obtained from original research in biochemistry and biomaterials science supporting the role of silicon in bone, comparing both the biological function of the element and analysing the evolution of silicon-containing biommaterials.
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Combination of Injectable Multiple Growth Factor–Releasing Scaffolds and Cell Therapy as an Advanced Modality to Enhance Tissue Neovascularization
Jaimy Saif,Theresa M. Schwarz,David Y.S. Chau,James R. Henstock,Paramjit Sami,Simon F. Leicht,Patrick C. Hermann,Sonia Alcalá,Francisca Mulero,Kevin M. Shakesheff,Christopher Heeschen,Alexandra Aicher +11 more
TL;DR: Combined use of scaffold-released growth factors and cell therapy improves neovascularization in ischemic diseases and may translate into more pronounced clinical effects.
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Remotely Activated Mechanotransduction via Magnetic Nanoparticles Promotes Mineralization Synergistically With Bone Morphogenetic Protein 2: Applications for Injectable Cell Therapy
TL;DR: The combination of mechanical stimulation and sustained release of bone morphogenetic protein 2 (BMP2) from polymer microspheres showed a significant additive effect on mineralization, increasing the effectiveness of BMP2 delivery and demonstrating that nanoparticle‐mediated mechanotransduction can be used synergistically with pharmacological approaches for orthopedic tissue engineering to maximize bone formation.
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Cyclic hydrostatic pressure stimulates enhanced bone development in the foetal chick femur in vitro.
TL;DR: It is demonstrated that cyclic hydrostatic pressure promotes bone growth and mineralisation in a developmental model and supports the hypothesis that hydrostatic forces play an important role in regulatingBone growth and remodelling in vivo.