James R. Merson

TL;DR: The results indicate that GS 4104 is a novel, orally active antiviral agent with the potential to be used for the prophylaxis and treatment of influenza A and B virus infections.

TL;DR: Results demonstrate that GS 4104 is an orally bioavailable prodrug of GS 4071 in animals and that it has the potential to be an oral agent for the prevention and treatment of influenza A and B virus infections in humans.

TL;DR: A chimeric vector combining the AAV capsid protein and the variable region of a single-chain antibody against human CD34 molecules, a cell surface marker for hematopoietic stem/progenitor cells is engineered and significantly increased the preferential infectivity of rAAV for the CD34+ human myoleukemia cell line KG-1.

TL;DR: In this article, an assay tray assembly and an assay trays primarily for chromatographic analysis has a plastics moulded test tray 1 mounted on a plastics molded collection tray 72, the test tray has a spaced array of chambers 3 disposed as per a microtiter plate, each chamber has a bottom outlet port 5 formed by a flange 8 which retains within the chamber a chromatograph medium to which test liquid deposited in the chamber is to be subjected for the percolate or eluate liquid to emerge from the respective outlet ports, the collection tray has an array

TL;DR: It is demonstrated that immune responses induced in mice by nicotine-conjugate antigens are greatly influenced by hapten design including site of attachment of linker to nicotine, the nature of linkers used, and the handle used to attach the haptens to DT.