James R Smith

TL;DR: Using single-cell RNA sequencing, the transcriptomes of cells from the proximal and non-proximal tubules of healthy and fibrotic human kidneys are profiled to map the entire human kidney and identify distinct subpopulations of pericytes and fibroblasts as the main cellular sources of scar-forming myofibro Blasts during human kidney fibrosis.

TL;DR: Patients blinded to whether they were receiving HD or HDF in a randomized controlled crossover study reported similar posttreatment recovery times and health-related quality-of-life scores.

TL;DR: In this article, the authors used the Pdgfrb-BAC-eGFP transgenic reporter mouse in combination with bulk and single-cell RNA sequencing to redefine the endometrial mesenchyme.

TL;DR: The Pdgfrb-BAC-eGFP transgenic reporter mouse is used in combination with bulk and single cell RNA sequencing to redefine the endometrial mesenchyme and provide the first to provide a single cell atlas of the mesenchymal cell landscape in mouse endometrium.

TL;DR: Early remission of proteinuria and the absence of early acute kidney injury (AKI) were associated with lower rates of death and ESKD.