J
Jan C.A. Hoorntje
Researcher at Maastricht University
Publications - 128
Citations - 8152
Jan C.A. Hoorntje is an academic researcher from Maastricht University. The author has contributed to research in topics: Myocardial infarction & Percutaneous coronary intervention. The author has an hindex of 42, co-authored 127 publications receiving 7608 citations. Previous affiliations of Jan C.A. Hoorntje include Maastricht University Medical Centre & Academic Medical Center.
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Journal ArticleDOI
Percutaneous Coronary Intervention of Functionally Nonsignificant Stenosis: 5-Year Follow-Up of the DEFER Study
Nico H.J. Pijls,Pepijn van Schaardenburgh,Ganesh Manoharan,Eric Boersma,Jan-Willem Bech,Marcel van 't Veer,Frits W. Bär,Jan C.A. Hoorntje,Jacques J. Koolen,William Wijns,Bernard De Bruyne +10 more
TL;DR: Five-year outcome after deferral of PCI of an intermediate coronary stenosis based on FFR >/=0.75 is excellent and the risk of cardiac death or myocardial infarction related to this stenosis is <1% per year and not decreased by stenting.
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Fractional Flow Reserve to Determine the Appropriateness of Angioplasty in Moderate Coronary Stenosis A Randomized Trial
G. Jan Willem Bech,Bernard De Bruyne,Nico H.J. Pijls,Ebo D. de Muinck,Jan C.A. Hoorntje,Javier Escaned,Pieter R. Stella,Eric Boersma,Jozef Bartunek,Jacques J. Koolen,William Wijns +10 more
TL;DR: Coronary pressure–derived fractional flow reserve (FFR) is an invasive index of stenosis severity that is a reliable substitute for noninvasive stress testing and identifies stenoses with hemodynamic significance.
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Symptom-onset-to-balloon time and mortality in patients with acute myocardial infarction treated by primary angioplasty.
Giuseppe De Luca,Harry Suryapranata,Felix Zijlstra,Arnoud W J van 't Hof,Jan C.A. Hoorntje,A T Marcel Gosselink,Jan Henk Dambrink,Menko-Jan de Boer +7 more
TL;DR: It is shown that, in patients with STEMI treated by primary angioplasty, symptom-onset-to-balloon time, but not door- to-balloons time, is related to mortality, particularly in non-low-risk patients and in the absence of preprocedural anterograde flow.
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Angiographic Assessment of Reperfusion in Acute Myocardial Infarction by Myocardial Blush Grade
José P.S. Henriques,Felix Zijlstra,Arnoud W J van 't Hof,Menko-Jan de Boer,Jan-Henk E. Dambrink,Marcel Gosselink,Jan C.A. Hoorntje,Harry Suryapranata +7 more
TL;DR: MBG is a strong angiographic predictor of mortality in patients with TIMI 3 flow after primary angioplasty and should include both TIMi 3 flow and MBG 2 or 3 in the definition of successful reperfusion.
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Reperfusion therapy in elderly patients with acute myocardial infarction: a randomized comparison of primary angioplasty and thrombolytic therapy.
Menko-Jan de Boer,J. P. Ottervanger,Arnoud W J van 't Hof,Jan C.A. Hoorntje,Harry Suryapranata,Felix Zijlstra +5 more
TL;DR: In this series of patients with AMI who were older than 75 years, primary coronary angioplasty had a significant clinical benefit when compared with IV streptokinase therapy.