Jan Gerris

TL;DR: The findings illustrate the importance of PLCzeta during fertilization and suggest that mutant forms of P LCzeta may underlie certain types of human male infertility.

TL;DR: Application of AOA results in normal fertilization and pregnancy rates in patients whose spermatozoa show deficient activation, and when MOAT reveals no activation deficiency in spermutozoa, AOA still allows for high fertilized and acceptable pregnancy rates.

TL;DR: Temporary nuclear arrest of human GV oocytes with PDE3-I proved to be beneficial for obtaining normal spindle and chromosome configurations after IVM, and resulted also in synchronization within the population of Gv oocytes.

TL;DR: ICSI-AOA is very efficient in patients with a suspected oocyte-related activation deficiency and previous TFF after conventional ICSI, and should be tested on half of the sibling oocytes to help distinguish between a molecular oocytes-relatedactivation deficiency and a previous technical or other biological failure.

TL;DR: This is the first report describing development of cloned human embryos using IVM oocytes and non-autologous transfer using a conventional method of SCNT.