P
P. De Sutter
Researcher at Ghent University Hospital
Publications - 144
Citations - 5427
P. De Sutter is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Intracytoplasmic sperm injection & Oocyte. The author has an hindex of 42, co-authored 139 publications receiving 4879 citations. Previous affiliations of P. De Sutter include Vrije Universiteit Brussel & Ghent University.
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Journal ArticleDOI
Reduced amounts and abnormal forms of phospholipase C zeta (PLCzeta) in spermatozoa from infertile men.
Elke Heytens,John Parrington,Kevin Coward,Kevin Coward,C Young,S Lambrecht,Sook-Young Yoon,Rafael A. Fissore,R. Hamer,Charlotte M. Deane,Margarida Ruas,P Grasa,R. Soleimani,Claude Cuvelier,Jan Gerris,Marc Dhont,Dieter Deforce,Luc Leybaert,P. De Sutter +18 more
TL;DR: The findings illustrate the importance of PLCzeta during fertilization and suggest that mutant forms of P LCzeta may underlie certain types of human male infertility.
Journal ArticleDOI
Oocyte activation, phospholipase C zeta and human infertility
TL;DR: The current understanding of human oocyte activation failure is summarized and recent discoveries linking certain cases of male infertility with defects in PLCζ expression and activity are described.
Journal ArticleDOI
In-vitro maturation of human germinal vesicle stage oocytes: role of cumulus cells and epidermal growth factor in the culture medium.
TL;DR: In this article, the authors investigated the effect of supplementation of the medium with gonadotrophins, oestradiol and epidermal growth factor (EGF) on the nuclear and cytoplasmic maturation of immature oocytes.
Journal ArticleDOI
Treatment option for sperm- or oocyte-related fertilization failure: assisted oocyte activation following diagnostic heterologous ICSI
TL;DR: Assisted oocyte activation by Ca-ionophore treatment can initiate fertilization in subsequent therapeutic ICSI and enables normal fertilization and pregnancy in sperm- and oocyte-related fertilization failure.
Journal ArticleDOI
A real‐life prospective health economic study of elective single embryo transfer versus two‐embryo transfer in first IVF/ICSI cycles
Jan Gerris,P. De Sutter,Diane De Neubourg,E Van Royen,J Vander Elst,K Mangelschots,M Vercruyssen,P Kok,Monique Elseviers,Lieven Annemans,P Pauwels,Marc Dhont +11 more
TL;DR: This prospective health economic study shows that transfer of a single top quality embryo is equally effective as, but substantially cheaper than, double embryo transfer in women <38 years of age in their first IVF/ICSI cycle.