J
Jane Somerville
Researcher at Imperial College London
Publications - 57
Citations - 6034
Jane Somerville is an academic researcher from Imperial College London. The author has contributed to research in topics: Heart disease & GUCH. The author has an hindex of 29, co-authored 57 publications receiving 5771 citations. Previous affiliations of Jane Somerville include National Institutes of Health.
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Journal ArticleDOI
Task Force 1: The Changing Profile of Congenital Heart Disease in Adult Life
Carole A. Warnes,Richard R. Liberthson,Gordon K. Danielson,Annie Dore,Louise Harris,Julien I. E. Hoffman,Jane Somerville,Roberta G. Williams,Gary D. Webb +8 more
TL;DR: The extraordinary advances in cardiac surgery, intensive care, and noninvasive diagnosis over the last 50 years have led to an enormous growth in the U.S. and throughout the world in the number of adults with congenital heart disease.
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Mechanoelectrical interaction in tetralogy of Fallot. QRS prolongation relates to right ventricular size and predicts malignant ventricular arrhythmias and sudden death.
TL;DR: Chronic right ventricular volume overload after tetralogy of Fallot repair is related to diastolic function and correlated with QRS prolongation and the risk of symptomatic arrhythmia is high when markedright ventricular enlargement and QRS prolongedation develop.
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Eisenmenger syndrome. Factors relating to deterioration and death
Luciano Daliento,Jane Somerville,Patrizia Presbitero,L. Menti,S. Brach-Prever,Giulio Rizzoli,S. Stone +6 more
TL;DR: Deterioration in Ability Index (worsening symptoms), age, complex defects, blood creatinine level, right ventricular dysfunction and non-cardiac surgery were variables which affected the prognosis adversely with uni- and multivariate analysis.
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Pregnancy in cyanotic congenital heart disease. Outcome of mother and fetus.
Patrizia Presbitero,Jane Somerville,Susan Stone,Erio Aruta,David Spiegelhalter,Filippo Rabajoli +5 more
TL;DR: Univariate analysis suggested that maternal disease, Ability Index, hemoglobin, and arterial oxygen saturation before the pregnancy were factors that discriminated between successful and unsuccessful fetal outcome, with hemoglobin and arterials oxygen saturation being the most important predictors.
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Ebstein's anomaly: presentation and outcome from fetus to adult.
David S. Celermajer,Catherine Bull,Janice A. Till,Seamus Cullen,Vassilios P. Vassillikos,Ian D. Sullivan,Lindsey D. Allan,Petros Nihoyannopoulos,Jane Somerville,John E. Deanfield +9 more
TL;DR: In Ebstein's anomaly, fetal and neonatal presentation is associated with a poor outcome and can be predicted by the echocardiographic appearance and presence of associated lesions, in older children and adults.