J
Janine T. Bossé
Researcher at Imperial College London
Publications - 83
Citations - 2584
Janine T. Bossé is an academic researcher from Imperial College London. The author has contributed to research in topics: Actinobacillus pleuropneumoniae & Gene. The author has an hindex of 28, co-authored 75 publications receiving 2244 citations. Previous affiliations of Janine T. Bossé include Ontario Veterinary College & University of Guelph.
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Journal ArticleDOI
Actinobacillus pleuropneumoniae: pathobiology and pathogenesis of infection.
Janine T. Bossé,Håkan Janson,Brian J. Sheehan,Amanda Beddek,Andrew N. Rycroft,J. Simon Kroll,Paul R. Langford +6 more
TL;DR: This review considers how adhesins, iron-acquisition factors, capsule and lipopolysaccharide, RTX cytotoxins and other potential future vaccine components contribute to colonisation, to avoidance of host clearance mechanisms and to damage of host tissues.
Journal ArticleDOI
Actinobacillus pleuropneumoniae RTX-toxins: uniform designation of haemolysins, cytolysins, pleurotoxin and their genes.
Joachim Frey,Janine T. Bossé,Y.-F. Chang,Janice M. Cullen,B. Fenwick,Gerald-F. Gerlach,D. Gygi,Freddy Haesebrouck,Thomas J. Inzana,R. Jansen,E. M. Kamp,Julie Macdonald,Janet I. MacInnes,Khyali R. Mittal,Jacques Nicolet,Andrew N. Rycroft,Ruud Philip Antoon Maria Segers,Mari A. Smits,E. Stenbaek,Douglas K. Struck,J. F. van den Bosch,P. J. Willson,Ry Young +22 more
TL;DR: The three different pore-forming RTX-toxins of Actinobacillus pleuropneumoniae are reviewed, and new and uniform designations for these toxins and their genes are proposed.
Journal ArticleDOI
Evolution of competence and DNA uptake specificity in the Pasteurellaceae.
Rosemary J. Redfield,Wendy A Findlay,Janine T. Bossé,J. Simon Kroll,Andrew D. S. Cameron,John H. E. Nash +5 more
TL;DR: Competence and DNA uptake specificity are ancestral properties of the Pasteurellaceae, with divergent USSs and uptake specificity distinguishing only the two major subclades.
Journal ArticleDOI
Update on Actinobacillus pleuropneumoniae-knowledge, gaps and challenges.
Elena L. Sassu,Janine T. Bossé,T.J. Tobias,M. Gottschalk,Paul R. Langford,Isabel Hennig-Pauka +5 more
TL;DR: This review sums up published results and expert opinions, within the fields of pathogenesis, epidemiology, transmission, immune response to infection, as well as the main means of prevention, detection and control of porcine pleuropneumonia.
Journal ArticleDOI
Identification of Actinobacillus pleuropneumoniae Genes Important for Survival during Infection in Its Natural Host
Brian J. Sheehan,Janine T. Bossé,Amanda Beddek,Andrew N. Rycroft,J. Simon Kroll,Paul R. Langford +5 more
TL;DR: A total of 2,064 signature-tagged Tn10 transposon mutants were assembled into pools of 48 each, and used to inoculate pigs by the endotracheal route as mentioned in this paper.