Jason A. Burdick

TL;DR: A hyperelastic constrained-mixture model is employed to capture the nonlinear and time-dependent properties of these scaffolds when formed as single-fiber populations or in multipolymer composites, and it is demonstrated that by carefully selecting fiber populations with differing mechanical properties and altering the relative fraction of each, a wide range of mechanical properties can be achieved.

TL;DR: In situ crosslinking is developed that permits the printing of non-viscous, photocrosslinkable bioinks via the direct-curing of the bioink with light through a photopermeable capillary prior to deposition.

TL;DR: A step-wise hydrogel crosslinking technique is used, where macromolecules are crosslinked using a sequence of addition then UV light-mediated radicalCrosslinking, to generate hydrogels with tunable stiffness, which permits the investigation of HSC response to materials with diverse levels and spatially heterogeneous mechanical properties.

TL;DR: Investigation of the temporal effects of degradable hyaluronic acid (HA) hydrogels on global LV remodeling, infarct thinning and expansion, andinfarct stiffness in a porcine infarCT model for 12 weeks post-MI using MRI and FE modeling provides insight into the influence of injectable hydrogel therapies on myocardial structure and function post- MI.

TL;DR: In this article, a biocompatible polymer, poly(DL-lactic-co-glycolic)acid (PLGA), is used to form hollow microcapsules from monodisperse water-in-oil-inwater (W/O/W) double emulsions.