J
Jason A. Burdick
Researcher at University of Pennsylvania
Publications - 363
Citations - 42498
Jason A. Burdick is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Self-healing hydrogels & Tissue engineering. The author has an hindex of 103, co-authored 335 publications receiving 34137 citations. Previous affiliations of Jason A. Burdick include Duke University & University of Kentucky.
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Journal ArticleDOI
Injectable Granular Hydrogels with Multifunctional Properties for Biomedical Applications.
Joshua E. Mealy,Jennifer J. Chung,Heon-Ho Jeong,David Issadore,Daeyeon Lee,Pavan Atluri,Jason A. Burdick +6 more
TL;DR: Injectable hydrogels are useful for numerous biomedical applications, such as to introduce therapeutics into tissues or for 3D printing, and shear‐thinning and self‐healing granular hydrogel developed from microgels that interact via guest–host chemistry are developed.
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Engineering on the straight and narrow: the mechanics of nanofibrous assemblies for fiber-reinforced tissue regeneration.
Robert L. Mauck,Brendon M. Baker,Nandan L. Nerurkar,Jason A. Burdick,Wan-Ju Li,Rocky S. Tuan,Dawn M. Elliott +6 more
TL;DR: Applying the same mechanical framework for understanding native and engineered fiber-reinforced tissues provides a functional method for evaluating the utility and maturation of these unique engineered constructs.
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Hydrogels with Reversible Mechanics to Probe Dynamic Cell Microenvironments
Adrianne M. Rosales,Adrianne M. Rosales,Sebastián L. Vega,Frank W. DelRio,Jason A. Burdick,Kristi S. Anseth,Kristi S. Anseth +6 more
TL;DR: Haluronic acid-based substrates capable of sequential photodegradation and photoinitiated crosslinking reactions to soften and then stiffen the hydrogels over a physiologically relevant range of moduli are developed, rendering this platform amenable to studies of dynamic mechanics on cell behavior across many cell types and contexts.
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The control of stem cell morphology and differentiation by hydrogel surface wrinkles.
TL;DR: It is found that hMSCs attached to lamellar wrinkles spread by taking the shape of the pattern, exhibit high aspect ratios, and differentiate into an osteogenic lineage, in contrast, cells that attached inside the hexagonal patterns remain rounded with low spreading and differentiation into an adipogenic lineage.
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Recent advances in hydrogels for cartilage tissue engineering
TL;DR: This review summarises innovative approaches to engineer hydrogels towards cartilage repair, with an eye towards eventual clinical translation.