Javier Ibáñez

TL;DR: It is shown that non-myelodepleted NOD-scid IL2Rγnull mice engrafted with human erythrocytes support an infectious burden up to tenfold higher than that supported by engrafted NOD -scid β2microglobulinnull mice.

TL;DR: Bidimensional analysis using SYTO‐16 can be used to accurately measure the concentration of Plasmodium spp.‐infected erythrocytes in mice without complex sample preparation and was quantitatively equivalent to YOYO‐1.

TL;DR: A global multilateral collaborative project aimed at screening the significant chemical diversity within the antimalarial in vitro hits described in the literature is a feasible task.

TL;DR: The biological characterization of this chemical family with the generic name cyclopropyl carboxamides is described, showing that inhibition of their still unknown target has very favorable pharmacological consequences but the compounds themselves seem to select for resistance at a high frequency.