Jazi al Enezi

TL;DR: This work addresses the deficit in individual contribution of each photoreceptor class to irradiance responses using mice expressing human red cone opsin, and reveals an unexpectedly important role for rods in retinal circuitry upstream of mRGCs.

TL;DR: It is shown that pupillomotor and circadian responses of mice relying solely on melanopsin for their photosensitivity can indeed be accurately predicted using the 480-nm nomogram, and that measuring light in these terms predicts the melanopsIn response to light of divergent spectral composition much more reliably than other methods for quantifying irradiance or illuminance currently in widespread use.