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Robert J. Lucas
Researcher at University of Manchester
Publications - 165
Citations - 13788
Robert J. Lucas is an academic researcher from University of Manchester. The author has contributed to research in topics: Melanopsin & Intrinsically photosensitive retinal ganglion cells. The author has an hindex of 49, co-authored 155 publications receiving 12016 citations. Previous affiliations of Robert J. Lucas include Charing Cross Hospital & Imperial College London.
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Journal ArticleDOI
Melanopsin and rod/cone photoreceptive systems account for all major accessory visual functions in mice.
Samer Hattar,Robert J. Lucas,Nicholas Mrosovsky,Stewart Thompson,Ronald H. Douglas,Mark W. Hankins,Janis Lem,Martin Biel,Franz Hofmann,Russell G. Foster,King Wai Yau +10 more
TL;DR: The rod–cone and melanopsin systems together seem to provide all of the photic input for these accessory visual functions such as pupillary light reflex and circadian photo-entrainment.
Journal ArticleDOI
Measuring and using light in the melanopsin age
Robert J. Lucas,Stuart N. Peirson,David M. Berson,Timothy M. Brown,Howard M. Cooper,Charles A. Czeisler,Mariana G. Figueiro,Paul D. Gamlin,Steven W. Lockley,John O’Hagan,Luke L. A. Price,Ignacio Provencio,Debra J. Skene,George C. Brainard +13 more
TL;DR: A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers.
Journal ArticleDOI
Regulation of Mammalian Circadian Behavior by Non-rod, Non-cone, Ocular Photoreceptors
Melanie S. Freedman,Robert J. Lucas,Bobby G. Soni,Malcolm von Schantz,Marta Muñoz,Zoë K. David-Gray,Russell G. Foster +6 more
TL;DR: Neither rods nor cones are required for photoentrainment, and the murine eye contains additional photoreceptors that regulate the circadian clock.
Journal ArticleDOI
Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
TL;DR: In the mammalian retina, a small subset of retinal ganglion cells (RGCs) are intrinsically photosensitive, expressing the opsin-like protein melanopsin, and project to brain nuclei involved in non-image-forming visual functions such as pupillary light reflex and circadian photoentrainment as discussed by the authors.
Journal ArticleDOI
Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision
Ali D. Güler,Jennifer L. Ecker,Gurprit S. Lall,Shafiqul Haq,Cara M. Altimus,Hsi Wen Liao,Alun R. Barnard,Hugh Cahill,Tudor C. Badea,Haiqing Zhao,Mark W. Hankins,David M. Berson,Robert J. Lucas,King Wai Yau,Samer Hattar +14 more
TL;DR: It is indicated that light signals for irradiance detection are dissociated from pattern vision at the retinal ganglion cell level, and animals that cannot detect light for NIF functions are still capable of image formation.