J
Jean-Baptiste Rognoni
Researcher at Centre national de la recherche scientifique
Publications - 16
Citations - 470
Jean-Baptiste Rognoni is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Cellular differentiation & Cell culture. The author has an hindex of 10, co-authored 15 publications receiving 458 citations. Previous affiliations of Jean-Baptiste Rognoni include Aix-Marseille University.
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Journal ArticleDOI
Suramin inhibits cell growth and glycolytic activity and triggers differentiation of human colic adenocarcinoma cell clone HT29-D4
TL;DR: It is shown that suramin inhibits the growth of human colic adenocarcinoma cells HT29-D4 and rapidly induces their differentiation into enterocyte-like cells and that the glycolytic activity of the treated cells is lowered by 42%.
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α2β1-integrin signaling by itself controls G1/S transition in a human adenocarcinoma cell line (Caco-2): implication of NADPH oxidase-dependent production of ROS
TL;DR: A new integrin-signaling pathway in colon tumor cells involved in cell cycle regulation by the extracellular matrix is identified and identified via alpha2beta1-integrin ligation.
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Differentiation of human colon cancer cells changes the expression of β-tubulin isotypes and MAPs
G. Carles,Diane Braguer,Charles Dumontet,V Bourgarel,A. Gonçalves,M Sarrazin,Jean-Baptiste Rognoni,Claudette Briand +7 more
TL;DR: The results indicate that the composition of microtubules should be considered as one of the criteria involved in the response of tumour cells to chemotherapy with anti-microtubule agents.
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Induction of polarized apical expression and vectorial release of carcinoembryonic antigen (CEA) during the process of differentiation of HT29-D4 cells.
Jacques Fantini,Jean-Baptiste Rognoni,Jean-Michel Culouscou,Gilbert Pommier,Jacques Marvaldi,Alain Tirard +5 more
TL;DR: An essential property of the HT29‐D4 cell line is the fact that no cell loss occurs after the medium change, so that the differentiated cells can be considered as the true counterpart of the undifferentiated one.
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Effect of microtubule disruption on cell adhesion and spreading.
Azzeddine Kadi,Véronique Pichard,Maxime Lehmann,Claudette Briand,Diane Braguer,Jacques Marvaldi,Jean-Baptiste Rognoni,José Luis +7 more
TL;DR: Microtubule depolymerization appears to increase initial attachment of cells to extracellular matrix, while impeding subsequent cell spreading, as shown in HT29-D4 cell line adenocarcinoma.