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Jean G. Diodati

Researcher at Université de Montréal

Publications -  27
Citations -  1707

Jean G. Diodati is an academic researcher from Université de Montréal. The author has contributed to research in topics: Clopidogrel & Aspirin. The author has an hindex of 14, co-authored 27 publications receiving 1581 citations. Previous affiliations of Jean G. Diodati include Montreal Heart Institute.

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Journal ArticleDOI

Resistance to clopidogrel: a review of the evidence.

TL;DR: Because there is no single and validated platelet function assay to measure clopidogrel's antiplatelet effect, it is not justified to routinely look for clopIDogrel resistance in the clinical setting.
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A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease

TL;DR: Six major platelet function tests are not equally effective in measuring aspirin's antiplatelet effect and correlate poorly amongst themselves, and the clinical usefulness of the different assays to classify correctly patients as aspirin resistant remains undetermined.
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Comparison of four tests to assess inhibition of platelet function by clopidogrel in stable coronary artery disease patients

TL;DR: The assessment of platelet function inhibition by clopidogrel is highly test-specific, thus highlighting the need for unambiguous guidelines with respect to assay selection, as Platelet function assays are not interchangeable.
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Possibility of a rebound phenomenon following antiplatelet therapy withdrawal: a look at the clinical and pharmacological evidence.

TL;DR: The possibility of a pharmacological rebound phenomenon which could lead to adverse ischemic events is unveiled, and the warning against premature discontinuation of antiplatelet drugs issued in current guidelines is supported.